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Items: 7

1.

N-linked glycosylation of Kv1.2 voltage-gated potassium channel facilitates cell surface expression and enhances the stability of internalized channels.

Thayer DA, Yang SB, Jan YN, Jan LY.

J Physiol. 2016 Nov 15;594(22):6701-6713. doi: 10.1113/JP272394. Epub 2016 Aug 2.

2.

Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain.

Shcherbatko A, Rossi A, Foletti D, Zhu G, Bogin O, Galindo Casas M, Rickert M, Hasa-Moreno A, Bartsevich V, Crameri A, Steiner AR, Henningsen R, Gill A, Pons J, Shelton DL, Rajpal A, Strop P.

J Biol Chem. 2016 Jul 1;291(27):13974-86. doi: 10.1074/jbc.M116.725978. Epub 2016 Apr 22.

3.

Multivalent antiviral XTEN-peptide conjugates with long in vivo half-life and enhanced solubility.

Ding S, Song M, Sim BC, Gu C, Podust VN, Wang CW, McLaughlin B, Shah TP, Lax R, Gast R, Sharan R, Vasek A, Hartman MA, Deniston C, Srinivas P, Schellenberger V.

Bioconjug Chem. 2014 Jul 16;25(7):1351-9. doi: 10.1021/bc500215m. Epub 2014 Jun 23.

4.

Endogenous nuclear RNAi mediates behavioral adaptation to odor.

Juang BT, Gu C, Starnes L, Palladino F, Goga A, Kennedy S, L'Etoile ND.

Cell. 2013 Aug 29;154(5):1010-1022. doi: 10.1016/j.cell.2013.08.006.

5.

GLP2-2G-XTEN: a pharmaceutical protein with improved serum half-life and efficacy in a rat Crohn's disease model.

Alters SE, McLaughlin B, Spink B, Lachinyan T, Wang CW, Podust V, Schellenberger V, Stemmer WP.

PLoS One. 2012;7(11):e50630. doi: 10.1371/journal.pone.0050630. Epub 2012 Nov 26. Corrected and republished in: PLoS One. 2013;8(6). doi: 10.1371/annotation/5c7138bd-5602-466d-8daf-e75e0b7d7fdb.

6.

Gcg-XTEN: an improved glucagon capable of preventing hypoglycemia without increasing baseline blood glucose.

Geething NC, To W, Spink BJ, Scholle MD, Wang CW, Yin Y, Yao Y, Schellenberger V, Cleland JL, Stemmer WP, Silverman J.

PLoS One. 2010 Apr 14;5(4):e10175. doi: 10.1371/journal.pone.0010175.

7.

Peptide ligands specific to the oxidized form of Escherichia coli thioredoxin.

Scholle MD, Banach BS, Hamdan SM, Richardson CC, Kay BK.

Biochim Biophys Acta. 2008 Nov;1784(11):1735-41. doi: 10.1016/j.bbapap.2008.06.022. Epub 2008 Jul 11.

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