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Items: 1 to 20 of 106

1.

IFN-β signalling regulates RAW 264.7 macrophage activation, cytokine production, and killing activity.

Karimi Y, Giles EC, Vahedi F, Chew MV, Nham T, Loukov D, Lee AJ, Bowdish DM, Ashkar AA.

Innate Immun. 2019 Oct 15:1753425919878839. doi: 10.1177/1753425919878839. [Epub ahead of print] No abstract available.

PMID:
31615311
2.

Medroxyprogesterone acetate alters the vaginal microbiota and microenvironment in women and increases susceptibility to HIV-1 in humanized mice.

Wessels JM, Lajoie J, Cooper MIJH, Omollo K, Felker AM, Vitali D, Dupont HA, Nguyen PV, Mueller K, Vahedi F, Kimani J, Oyugi J, Cheruiyot J, Mungai JN, Deshiere A, Tremblay MJ, Mazzulli T, Stearns JC, Ashkar AA, Fowke KR, Surette MG, Kaushic C.

Dis Model Mech. 2019 Oct 23;12(10). pii: dmm039669. doi: 10.1242/dmm.039669.

3.

What Defines NK Cell Functional Fate: Phenotype or Metabolism?

Poznanski SM, Ashkar AA.

Front Immunol. 2019 Jun 19;10:1414. doi: 10.3389/fimmu.2019.01414. eCollection 2019. Review.

4.

Type I Interferon Receptor on NK Cells Negatively Regulates Interferon-γ Production.

Lee AJ, Mian F, Poznanski SM, Stackaruk M, Chan T, Chew MV, Ashkar AA.

Front Immunol. 2019 Jun 4;10:1261. doi: 10.3389/fimmu.2019.01261. eCollection 2019.

5.

Thermal Stabilization of Viral Vaccines in Low-Cost Sugar Films.

Leung V, Mapletoft J, Zhang A, Lee A, Vahedi F, Chew M, Szewczyk A, Jahanshahi-Anbuhi S, Ang J, Cowbrough B, Miller MS, Ashkar A, Filipe CDM.

Sci Rep. 2019 May 21;9(1):7631. doi: 10.1038/s41598-019-44020-w.

6.

Statins Promote Interleukin-1β-Dependent Adipocyte Insulin Resistance Through Lower Prenylation, Not Cholesterol.

Henriksbo BD, Tamrakar AK, Xu J, Duggan BM, Cavallari JF, Phulka J, Stampfli MR, Ashkar AA, Schertzer JD.

Diabetes. 2019 Jul;68(7):1441-1448. doi: 10.2337/db18-0999. Epub 2019 Apr 22.

PMID:
31010959
7.

TLR2 Plays a Pivotal Role in Mediating Mucosal Serotonin Production in the Gut.

Wang H, Kwon YH, Dewan V, Vahedi F, Syed S, Fontes ME, Ashkar AA, Surette MG, Khan WI.

J Immunol. 2019 May 15;202(10):3041-3052. doi: 10.4049/jimmunol.1801034. Epub 2019 Apr 5.

PMID:
30952815
8.

Shining light on the significance of NK cell CD56 brightness.

Poznanski SM, Ashkar AA.

Cell Mol Immunol. 2018 Dec;15(12):1071-1073. doi: 10.1038/s41423-018-0163-3. Epub 2018 Oct 1. No abstract available.

9.

The Dual Nature of Type I and Type II Interferons.

Lee AJ, Ashkar AA.

Front Immunol. 2018 Sep 11;9:2061. doi: 10.3389/fimmu.2018.02061. eCollection 2018. Review.

10.

Immunometabolism of T cells and NK cells: metabolic control of effector and regulatory function.

Poznanski SM, Barra NG, Ashkar AA, Schertzer JD.

Inflamm Res. 2018 Oct;67(10):813-828. doi: 10.1007/s00011-018-1174-3. Epub 2018 Jul 31. Review.

PMID:
30066126
11.

Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model.

Poznanski SM, Nham T, Chew MV, Lee AJ, Hammill JA, Fan IY, Butcher M, Bramson JL, Lee DA, Hirte HW, Ashkar AA.

Cancer Immunol Res. 2018 Oct;6(10):1174-1185. doi: 10.1158/2326-6066.CIR-18-0144. Epub 2018 Jul 17.

12.

IL-15 and IFN-γ signal through the ERK pathway to inhibit HCV replication, independent of type I IFN signaling.

Vahedi F, Lee AJ, Collins SE, Chew MV, Lusty E, Chen B, Dubey A, Richards CD, Feld JJ, Russell RS, Mossman KL, Ashkar AA.

Cytokine. 2019 Dec;124:154439. doi: 10.1016/j.cyto.2018.06.006. Epub 2018 Jun 19.

PMID:
29908921
13.

Transforming the prostatic tumor microenvironment with oncolytic virotherapy.

Atherton MJ, Stephenson KB, Tzelepis F, Bakhshinyan D, Nikota JK, Son HH, Jirovec A, Lefebvre C, Dvorkin-Gheva A, Ashkar AA, Wan Y, Stojdl DF, Belanger EC, Breau RH, Bell JC, Saad F, Singh SK, Diallo JS, Lichty BD.

Oncoimmunology. 2018 Mar 27;7(7):e1445459. doi: 10.1080/2162402X.2018.1445459. eCollection 2018.

14.

Interferon-β induced in female genital epithelium by HIV-1 glycoprotein 120 via Toll-like-receptor 2 pathway acts to protect the mucosal barrier.

Nazli A, Dizzell S, Zahoor MA, Ferreira VH, Kafka J, Woods MW, Ouellet M, Ashkar AA, Tremblay MJ, Bowdish DM, Kaushic C.

Cell Mol Immunol. 2019 Feb;16(2):178-194. doi: 10.1038/cmi.2017.168. Epub 2018 Mar 19.

15.

High Intensity Interval Training Increases Natural Killer Cell Number and Function in Obese Breast Cancer-challenged Mice and Obese Women.

Barra NG, Fan IY, Gillen JB, Chew M, Marcinko K, Steinberg GR, Gibala MJ, Ashkar AA.

J Cancer Prev. 2017 Dec;22(4):260-266. doi: 10.15430/JCP.2017.22.4.260. Epub 2017 Dec 30.

16.

Ex vivo-expanded NK cells from blood and ascites of ovarian cancer patients are cytotoxic against autologous primary ovarian cancer cells.

Nham T, Poznanski SM, Fan IY, Shenouda MM, Chew MV, Lee AJ, Vahedi F, Karimi Y, Butcher M, Lee DA, Hirte H, Ashkar AA.

Cancer Immunol Immunother. 2018 Apr;67(4):575-587. doi: 10.1007/s00262-017-2112-x. Epub 2018 Jan 3.

PMID:
29299659
17.

Ex Vivo-expanded Natural Killer Cells Derived From Long-term Cryopreserved Cord Blood are Cytotoxic Against Primary Breast Cancer Cells.

Nham T, Poznanski SM, Fan IY, Vahedi F, Shenouda MM, Lee AJ, Chew MV, Hogg RT, Lee DA, Ashkar AA.

J Immunother. 2018 Feb/Mar;41(2):64-72. doi: 10.1097/CJI.0000000000000192.

PMID:
29189387
18.

Frequency of Human CD45+ Target Cells is a Key Determinant of Intravaginal HIV-1 Infection in Humanized Mice.

Nguyen PV, Wessels JM, Mueller K, Vahedi F, Anipindi V, Verschoor CP, Chew M, Deshiere A, Karniychuk U, Mazzulli T, Tremblay MJ, Ashkar AA, Kaushic C.

Sci Rep. 2017 Nov 10;7(1):15263. doi: 10.1038/s41598-017-15630-z.

19.

Ex Vivo Expanded Human NK Cells Survive and Proliferate in Humanized Mice with Autologous Human Immune Cells.

Vahedi F, Nham T, Poznanski SM, Chew MV, Shenouda MM, Lee D, Ashkar AA.

Sci Rep. 2017 Sep 21;7(1):12083. doi: 10.1038/s41598-017-12223-8.

20.

The Application of Humanized Mouse Models for the Study of Human Exclusive Viruses.

Vahedi F, Giles EC, Ashkar AA.

Methods Mol Biol. 2017;1656:1-56. doi: 10.1007/978-1-4939-7237-1_1.

PMID:
28808960

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