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Items: 1 to 20 of 148


Rear-polarized Wnt5a-receptor-actin-myosin-polarity (WRAMP) structures promote the speed and persistence of directional cell migration.

Connacher MK, Tay JW, Ahn NG.

Mol Biol Cell. 2017 Jun 7. pii: mbc.E16-12-0875. doi: 10.1091/mbc.E16-12-0875. [Epub ahead of print]


The Cac2 subunit is essential for productive histone binding and nucleosome assembly in CAF-1.

Mattiroli F, Gu Y, Balsbaugh JL, Ahn NG, Luger K.

Sci Rep. 2017 Apr 18;7:46274. doi: 10.1038/srep46274.


DNA-mediated association of two histone-bound complexes of yeast Chromatin Assembly Factor-1 (CAF-1) drives tetrasome assembly in the wake of DNA replication.

Mattiroli F, Gu Y, Yadav T, Balsbaugh JL, Harris MR, Findlay ES, Liu Y, Radebaugh CA, Stargell LA, Ahn NG, Whitehouse I, Luger K.

Elife. 2017 Mar 18;6. pii: e22799. doi: 10.7554/eLife.22799.


The Cac1 subunit of histone chaperone CAF-1 organizes CAF-1-H3/H4 architecture and tetramerizes histones.

Liu WH, Roemer SC, Zhou Y, Shen ZJ, Dennehey BK, Balsbaugh JL, Liddle JC, Nemkov T, Ahn NG, Hansen KC, Tyler JK, Churchill ME.

Elife. 2016 Sep 30;5. pii: e18023. doi: 10.7554/eLife.18023.


Variants of the yeast MAPK Mpk1 are fully functional independently of activation loop phosphorylation.

Goshen-Lago T, Goldberg-Carp A, Melamed D, Darlyuk-Saadon I, Bai C, Ahn NG, Admon A, Engelberg D.

Mol Biol Cell. 2016 Sep 1;27(17):2771-83. doi: 10.1091/mbc.E16-03-0167. Epub 2016 Jul 13.


p38β Mitogen-Activated Protein Kinase Modulates Its Own Basal Activity by Autophosphorylation of the Activating Residue Thr180 and the Inhibitory Residues Thr241 and Ser261.

Beenstock J, Melamed D, Mooshayef N, Mordechay D, Garfinkel BP, Ahn NG, Admon A, Engelberg D.

Mol Cell Biol. 2016 May 2;36(10):1540-54. doi: 10.1128/MCB.01105-15. Print 2016 May 15.


Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition.

Lee SM, Bae BS, Park HW, Ahn NG, Cho BG, Cho YL, Kwak YS.

J Ginseng Res. 2015 Oct;39(4):384-91. doi: 10.1016/j.jgr.2015.04.009. Epub 2015 May 11. Review.


Intrinsically active variants of Erk oncogenically transform cells and disclose unexpected autophosphorylation capability that is independent of TEY phosphorylation.

Smorodinsky-Atias K, Goshen-Lago T, Goldberg-Carp A, Melamed D, Shir A, Mooshayef N, Beenstock J, Karamansha Y, Darlyuk-Saadon I, Livnah O, Ahn NG, Admon A, Engelberg D.

Mol Biol Cell. 2016 Mar 15;27(6):1026-39. doi: 10.1091/mbc.E15-07-0521. Epub 2015 Dec 10.


A synthetic modular approach for modeling the role of the 3D microenvironment in tumor progression.

Singh SP, Schwartz MP, Tokuda EY, Luo Y, Rogers RE, Fujita M, Ahn NG, Anseth KS.

Sci Rep. 2015 Dec 7;5:17814. doi: 10.1038/srep17814.


Erratum to: Large-Scale Examination of Factors Influencing Phosphopeptide Neutral Loss During Collision Induced Dissociation.

Brown R, Stuart SA, Houel S, Ahn NG, Old WM.

J Am Soc Mass Spectrom. 2015 Oct;26(10):1796. doi: 10.1007/s13361-015-1222-y. No abstract available.


Structure-Based Assignment of Ile, Leu, and Val Methyl Groups in the Active and Inactive Forms of the Mitogen-Activated Protein Kinase Extracellular Signal-Regulated Kinase 2.

Xiao Y, Warner LR, Latham MP, Ahn NG, Pardi A.

Biochemistry. 2015 Jul 21;54(28):4307-19. doi: 10.1021/acs.biochem.5b00506. Epub 2015 Jul 13.


Large-Scale Examination of Factors Influencing Phosphopeptide Neutral Loss during Collision Induced Dissociation.

Brown R, Stuart SA, Houel S, Ahn NG, Old WM.

J Am Soc Mass Spectrom. 2015 Jul;26(7):1128-42. doi: 10.1007/s13361-015-1109-y. Epub 2015 Apr 8. Erratum in: J Am Soc Mass Spectrom. 2015 Oct;26(10):1796. Stuart, Scott S [corrected to Stuart, Scott A].


A Phosphoproteomic Comparison of B-RAFV600E and MKK1/2 Inhibitors in Melanoma Cells.

Stuart SA, Houel S, Lee T, Wang N, Old WM, Ahn NG.

Mol Cell Proteomics. 2015 Jun;14(6):1599-615. doi: 10.1074/mcp.M114.047233. Epub 2015 Apr 7.


Dynamics of protein kinases: insights from nuclear magnetic resonance.

Xiao Y, Liddle JC, Pardi A, Ahn NG.

Acc Chem Res. 2015 Apr 21;48(4):1106-14. doi: 10.1021/acs.accounts.5b00001. Epub 2015 Mar 24.


Identification of a family of fatty-acid-speciated sonic hedgehog proteins, whose members display differential biological properties.

Long J, Tokhunts R, Old WM, Houel S, Rodgriguez-Blanco J, Singh S, Schilling N, Capobianco AJ, Ahn NG, Robbins DJ.

Cell Rep. 2015 Mar 3;10(8):1280-7. doi: 10.1016/j.celrep.2015.01.058. Epub 2015 Feb 26.


Slow inhibition and conformation selective properties of extracellular signal-regulated kinase 1 and 2 inhibitors.

Rudolph J, Xiao Y, Pardi A, Ahn NG.

Biochemistry. 2015 Jan 13;54(1):22-31. doi: 10.1021/bi501101v. Epub 2014 Dec 4.


The p38β mitogen-activated protein kinase possesses an intrinsic autophosphorylation activity, generated by a short region composed of the α-G helix and MAPK insert.

Beenstock J, Ben-Yehuda S, Melamed D, Admon A, Livnah O, Ahn NG, Engelberg D.

J Biol Chem. 2014 Aug 22;289(34):23546-56. doi: 10.1074/jbc.M114.578237. Epub 2014 Jul 8.


Phosphorylation releases constraints to domain motion in ERK2.

Xiao Y, Lee T, Latham MP, Warner LR, Tanimoto A, Pardi A, Ahn NG.

Proc Natl Acad Sci U S A. 2014 Feb 18;111(7):2506-11. doi: 10.1073/pnas.1318899111. Epub 2014 Feb 3.


Extracellular-regulated kinase 2 is activated by the enhancement of hinge flexibility.

Sours KM, Xiao Y, Ahn NG.

J Mol Biol. 2014 May 1;426(9):1925-35. doi: 10.1016/j.jmb.2014.02.011. Epub 2014 Feb 15.


Programmed cell death protein 5 interacts with the cytosolic chaperonin containing tailless complex polypeptide 1 (CCT) to regulate β-tubulin folding.

Tracy CM, Gray AJ, Cuéllar J, Shaw TS, Howlett AC, Taylor RM, Prince JT, Ahn NG, Valpuesta JM, Willardson BM.

J Biol Chem. 2014 Feb 14;289(7):4490-502. doi: 10.1074/jbc.M113.542159. Epub 2013 Dec 27.

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