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Items: 1 to 20 of 248


Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin.

Larson AG, Elnatan D, Keenen MM, Trnka MJ, Johnston JB, Burlingame AL, Agard DA, Redding S, Narlikar GJ.

Nature. 2017 Jun 21. doi: 10.1038/nature22822. [Epub ahead of print]


Grafting both acute wound site and adjacent donor site with the same graft: an easy and safe procedure to improve healing and minimize pain in elderly and bedridden patients.

Keilani C, Agard D, Duhoux A, Lakhel A, Giraud O, Brachet M, Duhamel P, Bey E.

Ann Burns Fire Disasters. 2017 Mar 31;30(1):52-56.


MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy.

Zheng SQ, Palovcak E, Armache JP, Verba KA, Cheng Y, Agard DA.

Nat Methods. 2017 Apr;14(4):331-332. doi: 10.1038/nmeth.4193. Epub 2017 Feb 27. No abstract available.


Design of Allosteric Stimulators of the Hsp90 ATPase as New Anticancer Leads.

D'Annessa I, Sattin S, Tao J, Pennati M, Sànchez-Martìn C, Moroni E, Rasola A, Zaffaroni N, Agard DA, Bernardi A, Colombo G.

Chemistry. 2017 Apr 19;23(22):5188-5192. doi: 10.1002/chem.201700169. Epub 2017 Mar 22.


Assembly of a nucleus-like structure during viral replication in bacteria.

Chaikeeratisak V, Nguyen K, Khanna K, Brilot AF, Erb ML, Coker JK, Vavilina A, Newton GL, Buschauer R, Pogliano K, Villa E, Agard DA, Pogliano J.

Science. 2017 Jan 13;355(6321):194-197. doi: 10.1126/science.aal2130.


The effects of aminosalicylates or thiopurines on the risk of colorectal cancer in inflammatory bowel disease.

Carrat F, Seksik P, Colombel JF, Peyrin-Biroulet L, Beaugerie L; CESAME Study Group.

Aliment Pharmacol Ther. 2017 Feb;45(4):533-541. doi: 10.1111/apt.13897. Epub 2016 Dec 19.


Internal Structure and Preferential Protein Binding of Colloidal Aggregates.

Duan D, Torosyan H, Elnatan D, McLaughlin CK, Logie J, Shoichet MS, Agard DA, Shoichet BK.

ACS Chem Biol. 2017 Jan 20;12(1):282-290. doi: 10.1021/acschembio.6b00791. Epub 2016 Dec 16.


Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase.

Verba KA, Wang RY, Arakawa A, Liu Y, Shirouzu M, Yokoyama S, Agard DA.

Science. 2016 Jun 24;352(6293):1542-7. doi: 10.1126/science.aaf5023.


Higher-order oligomerization of Spc110p drives γ-tubulin ring complex assembly.

Lyon AS, Morin G, Moritz M, Yabut KC, Vojnar T, Zelter A, Muller E, Davis TN, Agard DA.

Mol Biol Cell. 2016 Jul 15;27(14):2245-58. doi: 10.1091/mbc.E16-02-0072. Epub 2016 May 25.


A Fortunate Story of an Unusual AK-47 Bullet Trajectory: Always Keep a Smartphone in Your Pocket.

Thabouillot O, Perrier P, Roche NC, Agard D, Barbier O, Martin G, Viant E, Leclere JB.

Prehosp Disaster Med. 2016 Jun;31(3):343-5. doi: 10.1017/S1049023X16000364. Epub 2016 Apr 18.


The Seckel syndrome and centrosomal protein Ninein localizes asymmetrically to stem cell centrosomes but is not required for normal development, behavior, or DNA damage response in Drosophila.

Zheng Y, Mennella V, Marks S, Wildonger J, Elnagdi E, Agard D, Megraw TL.

Mol Biol Cell. 2016 Jun 1;27(11):1740-52. doi: 10.1091/mbc.E15-09-0655. Epub 2016 Apr 6. Erratum in: Mol Biol Cell. 2016 Oct 15;27(20):3180.


Molecular Dynamics Simulations Reveal the Mechanisms of Allosteric Activation of Hsp90 by Designed Ligands.

Vettoretti G, Moroni E, Sattin S, Tao J, Agard DA, Bernardi A, Colombo G.

Sci Rep. 2016 Apr 1;6:23830. doi: 10.1038/srep23830.


Structure of γ-tubulin small complex based on a cryo-EM map, chemical cross-links, and a remotely related structure.

Greenberg CH, Kollman J, Zelter A, Johnson R, MacCoss MJ, Davis TN, Agard DA, Sali A.

J Struct Biol. 2016 Jun;194(3):303-10. doi: 10.1016/j.jsb.2016.03.006. Epub 2016 Mar 8.


Clinical validation of Anyplex™ II HPV HR Detection according to the guidelines for HPV test requirements for cervical cancer screening.

Hesselink AT, Sahli R, Berkhof J, Snijders PJ, van der Salm ML, Agard D, Bleeker MC, Heideman DA.

J Clin Virol. 2016 Mar;76:36-9. doi: 10.1016/j.jcv.2016.01.009. Epub 2016 Jan 15.


Excess risk of urinary tract cancers in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study.

Bourrier A, Carrat F, Colombel JF, Bouvier AM, Abitbol V, Marteau P, Cosnes J, Simon T, Peyrin-Biroulet L, Beaugerie L; CESAME study group.

Aliment Pharmacol Ther. 2016 Jan;43(2):252-61. doi: 10.1111/apt.13466. Epub 2015 Nov 9.


Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage.

Li X, Zheng S, Agard DA, Cheng Y.

J Struct Biol. 2015 Nov;192(2):174-8. doi: 10.1016/j.jsb.2015.09.003. Epub 2015 Sep 11.


Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic Inference.

Pimentel-Elardo SM, Sørensen D, Ho L, Ziko M, Bueler SA, Lu S, Tao J, Moser A, Lee R, Agard D, Fairn G, Rubinstein JL, Shoichet BK, Nodwell JR.

ACS Chem Biol. 2015 Nov 20;10(11):2616-23. doi: 10.1021/acschembio.5b00612. Epub 2015 Sep 18.


Evaluation of super-resolution performance of the K2 electron-counting camera using 2D crystals of aquaporin-0.

Chiu PL, Li X, Li Z, Beckett B, Brilot AF, Grigorieff N, Agard DA, Cheng Y, Walz T.

J Struct Biol. 2015 Nov;192(2):163-73. doi: 10.1016/j.jsb.2015.08.015. Epub 2015 Aug 28.


Activation of Hsp90 Enzymatic Activity and Conformational Dynamics through Rationally Designed Allosteric Ligands.

Sattin S, Tao J, Vettoretti G, Moroni E, Pennati M, Lopergolo A, Morelli L, Bugatti A, Zuehlke A, Moses M, Prince T, Kijima T, Beebe K, Rusnati M, Neckers L, Zaffaroni N, Agard DA, Bernardi A, Colombo G.

Chemistry. 2015 Sep 21;21(39):13598-608. doi: 10.1002/chem.201502211. Epub 2015 Aug 18.


The cancer cell map initiative: defining the hallmark networks of cancer.

Krogan NJ, Lippman S, Agard DA, Ashworth A, Ideker T.

Mol Cell. 2015 May 21;58(4):690-8. doi: 10.1016/j.molcel.2015.05.008. Review.

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