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Items: 17


Post-translational control of T cell development by the ESCRT protein CHMP5.

Adoro S, Park KH, Bettigole SE, Lis R, Shin HR, Seo H, Kim JH, Knobeloch KP, Shim JH, Glimcher LH.

Nat Immunol. 2017 Jul;18(7):780-790. doi: 10.1038/ni.3764. Epub 2017 May 29.


The transcription factor XBP1 is selectively required for eosinophil differentiation.

Bettigole SE, Lis R, Adoro S, Lee AH, Spencer LA, Weller PF, Glimcher LH.

Nat Immunol. 2015 Aug;16(8):829-37. doi: 10.1038/ni.3225. Epub 2015 Jul 6.


IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection.

Adoro S, Cubillos-Ruiz JR, Chen X, Deruaz M, Vrbanac VD, Song M, Park S, Murooka TT, Dudek TE, Luster AD, Tager AM, Streeck H, Bowman B, Walker BD, Kwon DS, Lazarevic V, Glimcher LH.

Nat Commun. 2015 Jun 25;6:7562. doi: 10.1038/ncomms8562.


XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway.

Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, Song M, Tan C, Landis MD, Ferrari M, Shin SJ, Brown M, Chang JC, Liu XS, Glimcher LH.

Nature. 2014 Apr 3;508(7494):103-107. doi: 10.1038/nature13119. Epub 2014 Mar 23.


A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells.

Fu W, Ergun A, Lu T, Hill JA, Haxhinasto S, Fassett MS, Gazit R, Adoro S, Glimcher L, Chan S, Kastner P, Rossi D, Collins JJ, Mathis D, Benoist C.

Nat Immunol. 2012 Oct;13(10):972-80. doi: 10.1038/ni.2420. Epub 2012 Sep 9.


Coreceptor gene "imprinting:" a genetic solution to a developmental dilemma in T cells.

Adoro S, Park JH, Singer A.

Cell Cycle. 2012 Mar 1;11(5):833-4. doi: 10.4161/cc.11.5.19596. Epub 2012 Mar 1. No abstract available.


Coreceptor gene imprinting governs thymocyte lineage fate.

Adoro S, McCaughtry T, Erman B, Alag A, Van Laethem F, Park JH, Tai X, Kimura M, Wang L, Grinberg A, Kubo M, Bosselut R, Love P, Singer A.

EMBO J. 2012 Jan 18;31(2):366-77. doi: 10.1038/emboj.2011.388. Epub 2011 Oct 28.


Signaling by intrathymic cytokines, not T cell antigen receptors, specifies CD8 lineage choice and promotes the differentiation of cytotoxic-lineage T cells.

Park JH, Adoro S, Guinter T, Erman B, Alag AS, Catalfamo M, Kimura MY, Cui Y, Lucas PJ, Gress RE, Kubo M, Hennighausen L, Feigenbaum L, Singer A.

Nat Immunol. 2010 Mar;11(3):257-64. doi: 10.1038/ni.1840. Epub 2010 Jan 31.


Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice.

Sarafova SD, Van Laethem F, Adoro S, Guinter T, Sharrow SO, Feigenbaum L, Singer A.

Immunity. 2009 Sep 18;31(3):480-90. doi: 10.1016/j.immuni.2009.07.006. Epub 2009 Sep 10.


Antibody specificities of children living in a malaria endemic area to inhibitory and blocking epitopes on MSP-1 19 of Plasmodium falciparum.

Omosun YO, Adoro S, Anumudu CI, Odaibo AB, Uthiapibull C, Holder AA, Nwagwu M, Nwuba RI.

Acta Trop. 2009 Mar;109(3):208-12. doi: 10.1016/j.actatropica.2008.11.011. Epub 2008 Nov 25.


Targeting CD4 coreceptor expression to postselection thymocytes reveals that CD4/CD8 lineage choice is neither error-prone nor stochastic.

Adoro S, Erman B, Sarafova SD, Van Laethem F, Park JH, Feigenbaum L, Singer A.

J Immunol. 2008 Nov 15;181(10):6975-83.


Lineage fate and intense debate: myths, models and mechanisms of CD4- versus CD8-lineage choice.

Singer A, Adoro S, Park JH.

Nat Rev Immunol. 2008 Oct;8(10):788-801. doi: 10.1038/nri2416. Review.


Deletion of CD4 and CD8 coreceptors permits generation of alphabetaT cells that recognize antigens independently of the MHC.

Van Laethem F, Sarafova SD, Park JH, Tai X, Pobezinsky L, Guinter TI, Adoro S, Adams A, Sharrow SO, Feigenbaum L, Singer A.

Immunity. 2007 Nov;27(5):735-50.


'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

Park JH, Adoro S, Lucas PJ, Sarafova SD, Alag AS, Doan LL, Erman B, Liu X, Ellmeier W, Bosselut R, Feigenbaum L, Singer A.

Nat Immunol. 2007 Oct;8(10):1049-59. Epub 2007 Sep 16.


Variation in the relationship between anti-MSP-1(19) antibody response and age in children infected with Plasmodium falciparum during the dry and rainy seasons.

Omosun YO, Anumudu CI, Adoro S, Odaibo AB, Sodeinde O, Holder AA, Nwagwu M, Nwuba RI.

Acta Trop. 2005 Sep;95(3):233-47.


Antimalarial drugs exacerbate rat liver microsomal lipid peroxidation in the presence of oxidants.

Farombi EO, Adoro S, Uhunmwangho S.

Biosci Rep. 2001 Jun;21(3):353-9.


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