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Anthracycline cardiotoxicity: looking for new therapeutic approaches targeting cell senescence?

Abid S, Lipskaia L, Adnot S.

Cardiovasc Res. 2018 Apr 28. doi: 10.1093/cvr/cvy108. [Epub ahead of print] No abstract available.


Visceral Adipose Tissue Drives Cardiac Aging Through Modulation of Fibroblast Senescence by Osteopontin Production.

Sawaki D, Czibik G, Pini M, Ternacle J, Suffee N, Mercedes R, Marcelin G, Surenaud M, Marcos E, Gual P, Clément K, Hue S, Adnot S, Hatem SN, Tsuchimochi I, Yoshimitsu T, Hénégar C, Derumeaux G.

Circulation. 2018 Mar 2. pii: CIRCULATIONAHA.117.031358. doi: 10.1161/CIRCULATIONAHA.117.031358. [Epub ahead of print]


New Nitric Oxide Donor NCX 1443: Therapeutic Effects on Pulmonary Hypertension in the SAD Mouse Model of Sickle Cell Disease.

Abid S, Kebe K, Houssaïni A, Tomberli F, Marcos E, Bizard E, Breau M, Parpaleix A, Tissot CM, Maitre B, Lipskaia L, Derumeaux G, Bastia E, Mekontso-Dessap A, Adnot S.

J Cardiovasc Pharmacol. 2018 May;71(5):283-292. doi: 10.1097/FJC.0000000000000570.


mTOR pathway activation drives lung cell senescence and emphysema.

Houssaini A, Breau M, Kebe K, Abid S, Marcos E, Lipskaia L, Rideau D, Parpaleix A, Huang J, Amsellem V, Vienney N, Validire P, Maitre B, Attwe A, Lukas C, Vindrieux D, Boczkowski J, Derumeaux G, Pende M, Bernard D, Meiners S, Adnot S.

JCI Insight. 2018 Feb 8;3(3). pii: 93203. doi: 10.1172/jci.insight.93203. [Epub ahead of print]


Beclin1 circulating levels and accelerated aging markers in COPD.

Schlemmer F, Boyer L, Soumagne T, Ridoux A, Chouaid C, Maitre B, Lanone S, Adnot S, Audureau E, Boczkowski J.

Cell Death Dis. 2018 Feb 5;9(2):156. doi: 10.1038/s41419-017-0178-1. No abstract available.


mTOR: A Key to Both Pulmonary Vessel Remodeling and Right Ventricular Function in Pulmonary Arterial Hypertension?

Houssaini A, Adnot S.

Am J Respir Cell Mol Biol. 2017 Nov;57(5):509-511. doi: 10.1165/rcmb.2017-0245ED. No abstract available.


Impaired humoral and cellular immune responses to influenza vaccination in chronic obstructive pulmonary disease patients.

Parpaleix A, Boyer L, Wiedemann A, Lacabaratz C, Margarit L, Enouf V, Le Corvoisier P, Lino A, Covali-Noroc A, Housset B, Chouaid C, Maitre B, Lévy Y, Lelièvre JD, Adnot S.

J Allergy Clin Immunol. 2017 Dec;140(6):1754-1757.e6. doi: 10.1016/j.jaci.2017.07.038. Epub 2017 Sep 7. No abstract available.


Smoking, telomere length and lung function decline: a longitudinal population-based study.

Andujar P, Courbon D, Bizard E, Marcos E, Adnot S, Boyer L, Demoly P, Jarvis D, Neukirch C, Pin I, Thabut G, Boczkowski J, Leynaert B.

Thorax. 2018 Mar;73(3):283-285. doi: 10.1136/thoraxjnl-2017-210294. Epub 2017 Jul 19.


Middle age exacerbates acute respiratory distress syndrome in a double hit murine model.

Voiriot G, Contou D, Tran Van Nhieu J, Amsellem V, Marcos E, Latiri M, Adnot S, Maitre B, Mekontso Dessap A.

Exp Gerontol. 2017 Oct 1;96:146-154. doi: 10.1016/j.exger.2017.06.022. Epub 2017 Jul 1.


Interleukin-6 displays lung anti-inflammatory properties and exerts protective hemodynamic effects in a double-hit murine acute lung injury.

Voiriot G, Razazi K, Amsellem V, Tran Van Nhieu J, Abid S, Adnot S, Mekontso Dessap A, Maitre B.

Respir Res. 2017 Apr 19;18(1):64. doi: 10.1186/s12931-017-0553-6.


Investigating hyperventilation syndrome in patients suffering from empty nose syndrome.

Mangin D, Bequignon E, Zerah-Lancner F, Isabey D, Louis B, Adnot S, Papon JF, Coste A, Boyer L, Devars du Mayne M.

Laryngoscope. 2017 Sep;127(9):1983-1988. doi: 10.1002/lary.26599. Epub 2017 Apr 13.


Telomere attrition in sickle cell anemia.

Mekontso Dessap A, Cecchini J, Chaar V, Marcos E, Habibi A, Bartolucci P, Ghaleh B, Galacteros F, Adnot S.

Am J Hematol. 2017 Jun;92(6):E112-E114. doi: 10.1002/ajh.24721. Epub 2017 Apr 18. No abstract available.


Roles for the CX3CL1/CX3CR1 and CCL2/CCR2 Chemokine Systems in Hypoxic Pulmonary Hypertension.

Amsellem V, Abid S, Poupel L, Parpaleix A, Rodero M, Gary-Bobo G, Latiri M, Dubois-Rande JL, Lipskaia L, Combadiere C, Adnot S.

Am J Respir Cell Mol Biol. 2017 May;56(5):597-608. doi: 10.1165/rcmb.2016-0201OC.


Short-term high-fat diet compromises myocardial function: a radial strain rate imaging study.

Ternacle J, Wan F, Sawaki D, Surenaud M, Pini M, Mercedes R, Ernande L, Audureau E, Dubois-Rande JL, Adnot S, Hue S, Czibik G, Derumeaux G.

Eur Heart J Cardiovasc Imaging. 2017 Nov 1;18(11):1283-1291. doi: 10.1093/ehjci/jew316.


Lack of information received by a French female cohort regarding prevention against exposure to reprotoxic agents during pregnancy.

Chabert MC, Perrin J, Berbis J, Bretelle F, Adnot S, Courbiere B.

Eur J Obstet Gynecol Reprod Biol. 2016 Oct;205:15-20. doi: 10.1016/j.ejogrb.2016.07.504. Epub 2016 Aug 3. Review.


A pilot study about infertile men's awareness of their reprotoxic exposures and the intervention of occupational medicine to assess them.

Christiaens A, Sari-Minodier I, Tardieu S, Ianos O, Adnot S, Courbiere B, Perrin J.

Basic Clin Androl. 2016 Aug 10;26:9. doi: 10.1186/s12610-016-0036-5. eCollection 2016.


Osteopontin, a Key Mediator Expressed by Senescent Pulmonary Vascular Cells in Pulmonary Hypertension.

Saker M, Lipskaia L, Marcos E, Abid S, Parpaleix A, Houssaini A, Validire P, Girard P, Noureddine H, Boyer L, Vienney N, Amsellem V, Marguerit L, Maitre B, Derumeaux G, Dubois-Rande JL, Jourdan-Lesaux C, Delcroix M, Quarck R, Adnot S.

Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1879-90. doi: 10.1161/ATVBAHA.116.307839. Epub 2016 Jul 21.


Role of interleukin-1 receptor 1/MyD88 signalling in the development and progression of pulmonary hypertension.

Parpaleix A, Amsellem V, Houssaini A, Abid S, Breau M, Marcos E, Sawaki D, Delcroix M, Quarck R, Maillard A, Couillin I, Ryffel B, Adnot S.

Eur Respir J. 2016 Aug;48(2):470-83. doi: 10.1183/13993003.01448-2015. Epub 2016 Jul 13.


Telomere Shortening in Middle-Aged Men with Sleep-disordered Breathing.

Boyer L, Audureau E, Margarit L, Marcos E, Bizard E, Le Corvoisier P, Macquin-Mavier I, Derumeaux G, Damy T, Drouot X, Covali-Noroc A, Boczkowski J, Bastuji-Garin S, Adnot S.

Ann Am Thorac Soc. 2016 Jul;13(7):1136-43. doi: 10.1513/AnnalsATS.201510-718OC.


Prevalence, Severity, and Prognostic Value of Sleep Apnea Syndromes in Cardiac Amyloidosis.

Bodez D, Guellich A, Kharoubi M, Covali-Noroc A, Tissot CM, Guendouz S, Hittinger L, Dubois-Randé JL, Lefaucheur JP, Planté-Bordeneuve V, Adnot S, Boyer L, Damy T.

Sleep. 2016 Jul 1;39(7):1333-41. doi: 10.5665/sleep.5958.

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