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AQP5-1364A/C polymorphism and the AQP5 expression influence sepsis survival and immune cell migration: a prospective laboratory and patient study.

Rump K, Unterberg M, Bergmann L, Bankfalvi A, Menon A, Schäfer S, Scherag A, Bazzi Z, Siffert W, Peters J, Adamzik M.

J Transl Med. 2016 Nov 21;14(1):321.


Hypoxia inducible factor-1 alpha and prolinhydroxlase 2 polymorphisms in patients with severe sepsis: a prospective observational trial.

Höcker A, Rabeling M, Bick A, Cox L, Kreuzer M, Engler A, Walstein K, Bachmann HS, Jöckel KH, Eisele L, Adamzik M, Peters J, Schäfer ST.

BMC Anesthesiol. 2016 Aug 11;16(1):61. doi: 10.1186/s12871-016-0225-y.


Phrenic nerve block caused by interscalene brachial plexus block: breathing effects of different sites of injection.

Bergmann L, Martini S, Kesselmeier M, Armbruster W, Notheisen T, Adamzik M, Eichholz R.

BMC Anesthesiol. 2016 Jul 29;16(1):45. doi: 10.1186/s12871-016-0218-x.


NFKB1 Promoter DNA from nt+402 to nt+99 Is Hypomethylated in Different Human Immune Cells.

Unterberg M, Kreuzer MJ, Schäfer ST, Bazzi Z, Adamzik M, Rump K.

PLoS One. 2016 Jun 1;11(6):e0156702. doi: 10.1371/journal.pone.0156702.


The Transcription Factor NMP4 Binds to the AQP5 Promoter and Is a Novel Transcriptional Regulator of the AQP5 Gene.

Rump K, Siffert W, Peters J, Adamzik M.

DNA Cell Biol. 2016 Jul;35(7):322-7. doi: 10.1089/dna.2015.3110.


Mitochondrial DNA: An Endogenous Trigger for Immune Paralysis.

Schäfer ST, Franken L, Adamzik M, Schumak B, Scherag A, Engler A, Schönborn N, Walden J, Koch S, Baba HA, Steinmann J, Westendorf AM, Fandrey J, Bieber T, Kurts C, Frede S, Peters J, Limmer A.

Anesthesiology. 2016 Apr;124(4):923-33. doi: 10.1097/ALN.0000000000001008.


Reply: PCR assay for pathogen detection in ventriculostomy-related meningitis in neurosurgery patients: unanswered questions?

Rath PM, Schoch B, Adamzik M, Steinmann E, Buer J, Steinmann J.

Infection. 2015 Apr;43(2):251-2. doi: 10.1007/s15010-015-0725-6. No abstract available.


Hydrocortisone fails to abolish NF-κB1 protein nuclear translocation in deletion allele carriers of the NFKB1 promoter polymorphism (-94ins/delATTG) and is associated with increased 30-day mortality in septic shock.

Schäfer ST, Gessner S, Scherag A, Rump K, Frey UH, Siffert W, Westendorf AM, Steinmann J, Peters J, Adamzik M.

PLoS One. 2014 Aug 18;9(8):e104953. doi: 10.1371/journal.pone.0104953. Erratum in: PLoS One. 2014;9(10):e112369.


Aquaporin 1 and 5 expression evoked by the β2 adrenoreceptor agonist terbutaline and lipopolysaccharide in mice and in the human monocytic cell line THP-1 is differentially regulated.

Rump K, Brendt P, Frey UH, Schäfer ST, Siffert W, Peters J, Adamzik M.

Shock. 2013 Nov;40(5):430-6. doi: 10.1097/SHK.0000000000000035.


The functional Aquaporin 1 -783G/C-polymorphism is associated with survival in patients with glioblastoma multiforme.

El Hindy N, Rump K, Lambertz N, Zhu Y, Frey UH, Bankfalvi A, Siffert W, Sure U, Peters J, Adamzik M, Sandalcioglu IE.

J Surg Oncol. 2013 Dec;108(7):492-8. doi: 10.1002/jso.23421.


An increased alveolar CD4 + CD25 + Foxp3 + T-regulatory cell ratio in acute respiratory distress syndrome is associated with increased 30-day mortality.

Adamzik M, Broll J, Steinmann J, Westendorf AM, Rehfeld I, Kreissig C, Peters J.

Intensive Care Med. 2013 Oct;39(10):1743-51. doi: 10.1007/s00134-013-3036-3.


Hypoxia-inducible factor and target gene expression are decreased in patients with sepsis: prospective observational clinical and cellular studies.

Schäfer ST, Frede S, Winning S, Bick A, Roshangar P, Fandrey J, Peters J, Adamzik M.

Anesthesiology. 2013 Jun;118(6):1426-36. doi: 10.1097/ALN.0b013e31828baa67.


Correlation of aquaporin-1 water channel protein expression with tumor angiogenesis in human astrocytoma.

El Hindy N, Bankfalvi A, Herring A, Adamzik M, Lambertz N, Zhu Y, Siffert W, Sure U, Sandalcioglu IE.

Anticancer Res. 2013 Feb;33(2):609-13.


Expression of aquaporin 5 and the AQP5 polymorphism A(-1364)C in association with peritumoral brain edema in meningioma patients.

Lambertz N, Hindy NE, Adler C, Rump K, Adamzik M, Keyvani K, Bankfalvi A, Siffert W, Erol Sandalcioglu I, Bachmann HS.

J Neurooncol. 2013 Apr;112(2):297-305. doi: 10.1007/s11060-013-1064-z.


The NFKB1 promoter polymorphism (-94ins/delATTG) alters nuclear translocation of NF-κB1 in monocytes after lipopolysaccharide stimulation and is associated with increased mortality in sepsis.

Adamzik M, Schäfer S, Frey UH, Becker A, Kreuzer M, Winning S, Frede S, Steinmann J, Fandrey J, Zacharowski K, Siffert W, Peters J, Hartmann M.

Anesthesiology. 2013 Jan;118(1):123-33. doi: 10.1097/ALN.0b013e318277a652.


Quantification of regulatory T cells in septic patients by real-time PCR-based methylation assay and flow cytometry.

Tatura R, Zeschnigk M, Adamzik M, Probst-Kepper M, Buer J, Kehrmann J.

PLoS One. 2012;7(11):e49962. doi: 10.1371/journal.pone.0049962.


Whole blood impedance aggregometry as a biomarker for the diagnosis and prognosis of severe sepsis.

Adamzik M, Görlinger K, Peters J, Hartmann M.

Crit Care. 2012 Oct 22;16(5):R204. doi: 10.1186/cc11816.


Recurrent false alarm of extracorporeal membrane oxygenation at high noon.

Dirkmann D, Kehren CJ, Adamzik M, Hofer C, Peters J, Herbstreit F.

Eur J Anaesthesiol. 2012 Dec;29(12):602-4. doi: 10.1097/EJA.0b013e3283598e7c. No abstract available.


Free hemoglobin concentration in severe sepsis: methods of measurement and prediction of outcome.

Adamzik M, Hamburger T, Petrat F, Peters J, de Groot H, Hartmann M.

Crit Care. 2012 Jul 16;16(4):R125. doi: 10.1186/cc11425.


The -1364A/C Aquaporin 5 Gene Promoter Polymorphism Is Not Associated with Menière's Disease.

Arweiler-Harbeck D, Saidi F, Lang S, Peters J, Siffert W, Adamzik M.

ISRN Otolaryngol. 2012 Oct 16;2012:706896. doi: 10.5402/2012/706896.

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