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Items: 1 to 20 of 743

1.

Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis.

Espana-Agusti J, Warren A, Chew SK, Adams DJ, Matakidou A.

Nat Commun. 2017 Dec 11;8(1):2026. doi: 10.1038/s41467-017-02245-1.

2.

Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing.

Bach K, Pensa S, Grzelak M, Hadfield J, Adams DJ, Marioni JC, Khaled WT.

Nat Commun. 2017 Dec 11;8(1):2128. doi: 10.1038/s41467-017-02001-5.

3.

Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence.

Singleton KR, Crawford L, Tsui E, Manchester HE, Maertens O, Liu X, Liberti MV, Magpusao AN, Stein EM, Tingley JP, Frederick DT, Boland GM, Flaherty KT, McCall SJ, Krepler C, Sproesser K, Herlyn M, Adams DJ, Locasale JW, Cichowski K, Mukherjee S, Wood KC.

Cell Rep. 2017 Dec 5;21(10):2796-2812. doi: 10.1016/j.celrep.2017.11.022.

4.

Widespread spontaneous hyperproliferation, melanosis and melanoma in Hgf-Cdk4R24C mice.

van der Weyden L, Arends MJ, Brenn T, Tuting T, Adams DJ.

Melanoma Res. 2017 Dec 1. doi: 10.1097/CMR.0000000000000414. [Epub ahead of print] No abstract available.

PMID:
29200095
5.

Cyclic analogues of α-conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain.

Castro J, Grundy L, Deiteren A, Harrington AM, O'Donnell T, Maddern J, Moore J, Garcia-Caraballo S, Rychkov GY, Yu R, Kaas Q, Craik DJ, Adams DJ, Brierley SM.

Br J Pharmacol. 2017 Nov 30. doi: 10.1111/bph.14115. [Epub ahead of print]

PMID:
29194563
6.

Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis.

Del Castillo Velasco-Herrera M, van der Weyden L, Nsengimana J, Speak AO, Sjöberg MK, Bishop DT, Jönsson G, Newton-Bishop J, Adams DJ.

Mol Oncol. 2017 Nov 29. doi: 10.1002/1878-0261.12161. [Epub ahead of print]

7.

Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors.

Durek T, Shelukhina IV, Tae HS, Thongyoo P, Spirova EN, Kudryavtsev DS, Kasheverov IE, Faure G, Corringer PJ, Craik DJ, Adams DJ, Tsetlin VI.

Sci Rep. 2017 Nov 30;7(1):16606. doi: 10.1038/s41598-017-16809-0.

8.

SPIONs for cell labelling and tracking using MRI: magnetite or maghemite?

Barrow M, Taylor A, Fuentes-Caparrós AM, Sharkey J, Daniels LM, Mandal P, Park BK, Murray P, Rosseinsky MJ, Adams DJ.

Biomater Sci. 2017 Nov 30. doi: 10.1039/c7bm00515f. [Epub ahead of print]

PMID:
29188240
9.

Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma.

Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J.

Nat Commun. 2017 Nov 28;8(1):1819. doi: 10.1038/s41467-017-01992-5.

10.

Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor.

Gorelenkova Miller O, Cole KS, Emerson CC, Allimuthu D, Golczak M, Stewart PL, Weerapana E, Adams DJ, Mieyal JJ.

PLoS One. 2017 Nov 20;12(11):e0187991. doi: 10.1371/journal.pone.0187991. eCollection 2017.

11.

Neuropharmacology of venom peptides.

Adams DJ, Lewis RJ.

Neuropharmacology. 2017 Dec;127:1-3. doi: 10.1016/j.neuropharm.2017.11.025. Epub 2017 Nov 14. No abstract available.

PMID:
29154773
12.

Corrigendum: High-throughput discovery of novel developmental phenotypes.

Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie Helmut Fuchs SM, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Nutter SNLMJ, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A; International Mouse Phenotyping Consortium, Wurst W, MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SDM, Adams DJ, Lloyd KCK, McKerlie C, Beaudet AL, Murray MBSA.

Nature. 2017 Nov 16;551(7680):398. doi: 10.1038/nature24643. Epub 2017 Nov 8.

PMID:
29144450
13.

A high-throughput in vivo screening method in the mouse for identifying regulators of metastatic colonization.

Speak AO, Swiatkowska A, Karp NA, Arends MJ, Adams DJ, van der Weyden L.

Nat Protoc. 2017 Dec;12(12):2465-2477. doi: 10.1038/nprot.2017.118. Epub 2017 Nov 2.

PMID:
29095442
14.

Optimising low molecular weight hydrogels for automated 3D printing.

Nolan MC, Fuentes Caparrós AM, Dietrich B, Barrow M, Cross ER, Bleuel M, King SM, Adams DJ.

Soft Matter. 2017 Nov 22;13(45):8426-8432. doi: 10.1039/c7sm01694h.

PMID:
29083003
15.

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bär S, Minocha S, Chevalier C, Po C; Sanger Mouse Genetics Project, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Hérault Y, Collins SC, Friant S, Godin JD, Yalcin B.

Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317. doi: 10.1073/pnas.1713625114. Epub 2017 Oct 12.

PMID:
29078390
16.

A large scale hearing loss screen reveals an extensive unexplored genetic landscape for auditory dysfunction.

Bowl MR, Simon MM, Ingham NJ, Greenaway S, Santos L, Cater H, Taylor S, Mason J, Kurbatova N, Pearson S, Bower LR, Clary DA, Meziane H, Reilly P, Minowa O, Kelsey L; International Mouse Phenotyping Consortium, Tocchini-Valentini GP, Gao X, Bradley A, Skarnes WC, Moore M, Beaudet AL, Justice MJ, Seavitt J, Dickinson ME, Wurst W, de Angelis MH, Herault Y, Wakana S, Nutter LMJ, Flenniken AM, McKerlie C, Murray SA, Svenson KL, Braun RE, West DB, Lloyd KCK, Adams DJ, White J, Karp N, Flicek P, Smedley D, Meehan TF, Parkinson HE, Teboul LM, Wells S, Steel KP, Mallon AM, Brown SDM.

Nat Commun. 2017 Oct 12;8(1):886. doi: 10.1038/s41467-017-00595-4.

17.

Sanger Institute series: uncovering the genetics of cancer: an interview with David Adams.

Adams DJ.

Future Oncol. 2017 Oct;13(24):2133-2135. doi: 10.2217/fon-2017-0312. Epub 2017 Oct 6.

PMID:
28984472
18.

Focusing of a Rydberg Positronium Beam with an Ellipsoidal Electrostatic Mirror.

Jones ACL, Moxom J, Rutbeck-Goldman HJ, Osorno KA, Cecchini GG, Fuentes-Garcia M, Greaves RG, Adams DJ, Tom HWK, Mills AP, Leventhal M.

Phys Rev Lett. 2017 Aug 4;119(5):053201. doi: 10.1103/PhysRevLett.119.053201. Epub 2017 Aug 2.

PMID:
28949762
19.

In vivo and in vitro testing of native α-conotoxins from the injected venom of Conus purpurascens.

Hoggard MF, Rodriguez AM, Cano H, Clark E, Tae HS, Adams DJ, Godenschwege TA, Marí F.

Neuropharmacology. 2017 Dec;127:253-259. doi: 10.1016/j.neuropharm.2017.09.020. Epub 2017 Sep 14.

PMID:
28917942
20.

Genome wide in vivo mouse screen data from studies to assess host regulation of metastatic colonisation.

van der Weyden L, Karp NA, Swiatkowska A, Adams DJ, Speak AO.

Sci Data. 2017 Sep 12;4:170129. doi: 10.1038/sdata.2017.129.

PMID:
28895944

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