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Items: 1 to 20 of 72


Ethanol Extract of Securidaca longipedunculata Induces Apoptosis in Brain Tumor (U87) Cells.

Ngulde SI, Sandabe UK, Abounader R, Dawson TK, Zhang Y, Iliya I, Hussaini IM.

Biomed Res Int. 2019 Feb 26;2019:9826590. doi: 10.1155/2019/9826590. eCollection 2019.


Myt1 and Myt1l transcription factors limit proliferation in GBM cells by repressing YAP1 expression.

Melhuish TA, Kowalczyk I, Manukyan A, Zhang Y, Shah A, Abounader R, Wotton D.

Biochim Biophys Acta Gene Regul Mech. 2018 Nov;1861(11):983-995. doi: 10.1016/j.bbagrm.2018.10.005. Epub 2018 Oct 10.


Discovery and Therapeutic Exploitation of Mechanisms of Resistance to MET Inhibitors in Glioblastoma.

Cruickshanks N, Zhang Y, Hine S, Gibert M, Yuan F, Oxford M, Grello C, Pahuski M, Dube C, Guessous F, Wang B, Deveau C, Saoud K, Gallagher I, Wulfkuhle J, Schiff D, Phan S, Petricoin E, Abounader R.

Clin Cancer Res. 2019 Jan 15;25(2):663-673. doi: 10.1158/1078-0432.CCR-18-0926. Epub 2018 Sep 10.


The p53 Pathway in Glioblastoma.

Zhang Y, Dube C, Gibert M Jr, Cruickshanks N, Wang B, Coughlan M, Yang Y, Setiady I, Deveau C, Saoud K, Grello C, Oxford M, Yuan F, Abounader R.

Cancers (Basel). 2018 Sep 1;10(9). pii: E297. doi: 10.3390/cancers10090297. Review.


Correction to: Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS, STAT5B, and glioblastoma.

Zhang Y, Kim J, Mueller AC, Dey B, Yang Y, Lee DH, Hachmann J, Finderle S, Park DM, Christensen J, Schiff D, Purow B, Dutta A, Abounader R.

Cell Death Differ. 2019 Jan;26(1):197. doi: 10.1038/s41418-018-0145-0.


Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma.

Olmez I, Zhang Y, Manigat L, Benamar M, Brenneman B, Nakano I, Godlewski J, Bronisz A, Lee J, Abbas T, Abounader R, Purow B.

Cancer Res. 2018 Aug 1;78(15):4360-4369. doi: 10.1158/0008-5472.CAN-17-3124. Epub 2018 May 29.


A new practical and versatile mouse model of proneural glioblastoma.

Abounader R.

Neuro Oncol. 2018 Feb 19;20(3):299-301. doi: 10.1093/neuonc/nox233. No abstract available.


p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression.

Gonzalez PP, Kim J, Galvao RP, Cruickshanks N, Abounader R, Zong H.

Glia. 2018 May;66(5):999-1015. doi: 10.1002/glia.23297. Epub 2018 Feb 2.


Noncoding RNAs in Glioblastoma.

Zhang Y, Cruickshanks N, Pahuski M, Yuan F, Dutta A, Schiff D, Purow B, Abounader R.

In: De Vleeschouwer S, editor. Glioblastoma [Internet]. Brisbane (AU): Codon Publications; 2017 Sep 27. Chapter 6.


Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha.

Olmez I, Love S, Xiao A, Manigat L, Randolph P, McKenna BD, Neal BP, Boroda S, Li M, Brenneman B, Abounader R, Floyd D, Lee J, Nakano I, Godlewski J, Bronisz A, Sulman EP, Mayo M, Gioeli D, Weber M, Harris TE, Purow B.

Neuro Oncol. 2018 Jan 22;20(2):192-202. doi: 10.1093/neuonc/nox119.


Combined CDK4/6 and mTOR Inhibition Is Synergistic against Glioblastoma via Multiple Mechanisms.

Olmez I, Brenneman B, Xiao A, Serbulea V, Benamar M, Zhang Y, Manigat L, Abbas T, Lee J, Nakano I, Godlewski J, Bronisz A, Abounader R, Leitinger N, Purow B.

Clin Cancer Res. 2017 Nov 15;23(22):6958-6968. doi: 10.1158/1078-0432.CCR-17-0803. Epub 2017 Aug 16.


Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma.

Cruickshanks N, Zhang Y, Yuan F, Pahuski M, Gibert M, Abounader R.

Cancers (Basel). 2017 Jul 11;9(7). pii: E87. doi: 10.3390/cancers9070087. Review.


Targetable T-type Calcium Channels Drive Glioblastoma.

Zhang Y, Cruickshanks N, Yuan F, Wang B, Pahuski M, Wulfkuhle J, Gallagher I, Koeppel AF, Hatef S, Papanicolas C, Lee J, Bar EE, Schiff D, Turner SD, Petricoin EF, Gray LS, Abounader R.

Cancer Res. 2017 Jul 1;77(13):3479-3490. doi: 10.1158/0008-5472.CAN-16-2347. Epub 2017 May 16.


Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis.

Reon BJ, Anaya J, Zhang Y, Mandell J, Purow B, Abounader R, Dutta A.

PLoS Med. 2016 Dec 6;13(12):e1002192. doi: 10.1371/journal.pmed.1002192. eCollection 2016 Dec.


Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma.

Lee DH, Zhang Y, Kassam AB, Park MJ, Gardner P, Prevedello D, Henry S, Horbinski C, Beumer JH, Tawbi H, Williams BJ, Shaffrey ME, Egorin MJ, Abounader R, Park DM.

PLoS One. 2015 Aug 6;10(8):e0134426. doi: 10.1371/journal.pone.0134426. eCollection 2015.


Targeting MET for glioma therapy.

Awad AJ, Burns TC, Zhang Y, Abounader R.

Neurosurg Focus. 2014 Dec;37(6):E10. doi: 10.3171/2014.9.FOCUS14520. Review.


Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim.

Floyd DH, Zhang Y, Dey BK, Kefas B, Breit H, Marks K, Dutta A, Herold-Mende C, Synowitz M, Glass R, Abounader R, Purow BW.

PLoS One. 2014 May 7;9(5):e96239. doi: 10.1371/journal.pone.0096239. eCollection 2014.


A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins.

Negishi M, Wongpalee SP, Sarkar S, Park J, Lee KY, Shibata Y, Reon BJ, Abounader R, Suzuki Y, Sugano S, Dutta A.

PLoS One. 2014 Apr 18;9(4):e95216. doi: 10.1371/journal.pone.0095216. eCollection 2014.


MicroRNA-608 and microRNA-34a regulate chordoma malignancy by targeting EGFR, Bcl-xL and MET.

Zhang Y, Schiff D, Park D, Abounader R.

PLoS One. 2014 Mar 12;9(3):e91546. doi: 10.1371/journal.pone.0091546. eCollection 2014.


Regulatory factor X1 is a new tumor suppressive transcription factor that acts via direct downregulation of CD44 in glioblastoma.

Feng C, Zhang Y, Yin J, Li J, Abounader R, Zuo Z.

Neuro Oncol. 2014 Aug;16(8):1078-85. doi: 10.1093/neuonc/nou010. Epub 2014 Feb 12.

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