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Items: 1 to 20 of 91


SOX2 Regulates P63 and Stem/Progenitor Cell State in the Corneal Epithelium.

Bhattacharya S, Serror L, Nir E, Dhiraj D, Altshuler A, Khreish M, Tiosano B, Hasson P, Panman L, Luxenburg C, Aberdam D, Shalom-Feuerstein R.

Stem Cells. 2018 Dec 10. doi: 10.1002/stem.2959. [Epub ahead of print]


Modeling of Aniridia-Related Keratopathy by CRISPR/Cas9 Genome Editing of Human Limbal Epithelial Cells and Rescue by Recombinant PAX6 Protein.

Roux LN, Petit I, Domart R, Concordet JP, Qu J, Zhou H, Joliot A, Ferrigno O, Aberdam D.

Stem Cells. 2018 Sep;36(9):1421-1429. doi: 10.1002/stem.2858. Epub 2018 Jul 18.


microRNA-184 Induces a Commitment Switch to Epidermal Differentiation.

Nagosa S, Leesch F, Putin D, Bhattacharya S, Altshuler A, Serror L, Amitai-Lange A, Nasser W, Aberdam E, Rouleau M, Tattikota SG, Poy MN, Aberdam D, Shalom-Feuerstein R.

Stem Cell Reports. 2017 Dec 12;9(6):1991-2004. doi: 10.1016/j.stemcr.2017.10.030. Epub 2017 Nov 30.


Induced pluripotent stem cell-derived limbal epithelial cells (LiPSC) as a cellular alternative for in vitro ocular toxicity testing.

Aberdam E, Petit I, Sangari L, Aberdam D.

PLoS One. 2017 Jun 22;12(6):e0179913. doi: 10.1371/journal.pone.0179913. eCollection 2017.


Pluripotent Stem Cells and Other Innovative Strategies for the Treatment of Ocular Surface Diseases.

Erbani J, Aberdam D, Larghero J, Vanneaux V.

Stem Cell Rev. 2016 Apr;12(2):171-8. doi: 10.1007/s12015-016-9643-y. Review.


Pluripotent stem cells as a cellular model for skin: relevance for physiopathology, cell/gene therapy and drug screening.

Levy A, Petit I, Aberdam D.

Eur J Dermatol. 2015 Apr;25 Suppl 1:12-7. Review.


[Metabolic switch in pluripotent stem cells: identification of a novel pathway].

Aberdam D.

Med Sci (Paris). 2015 Jun-Jul;31(6-7):581-3. doi: 10.1051/medsci/20153106002. Epub 2015 Jul 7. French. No abstract available.


RBM28, a protein deficient in ANE syndrome, regulates hair follicle growth via miR-203 and p63.

Warshauer E, Samuelov L, Sarig O, Vodo D, Bindereif A, Kanaan M, Gat U, Fuchs-Telem D, Shomron N, Farberov L, Pasmanik-Chor M, Nardini G, Winkler E, Meilik B, Petit I, Aberdam D, Paus R, Sprecher E, Nousbeck J.

Exp Dermatol. 2015 Aug;24(8):618-22. doi: 10.1111/exd.12737. Epub 2015 May 26.


Concise Review: Energy Metabolites: Key Mediators of the Epigenetic State of Pluripotency.

Moussaieff A, Kogan NM, Aberdam D.

Stem Cells. 2015 Aug;33(8):2374-80. doi: 10.1002/stem.2041. Epub 2015 May 26. Review.


Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.

Moussaieff A, Rouleau M, Kitsberg D, Cohen M, Levy G, Barasch D, Nemirovski A, Shen-Orr S, Laevsky I, Amit M, Bomze D, Elena-Herrmann B, Scherf T, Nissim-Rafinia M, Kempa S, Itskovitz-Eldor J, Meshorer E, Aberdam D, Nahmias Y.

Cell Metab. 2015 Mar 3;21(3):392-402. doi: 10.1016/j.cmet.2015.02.002.


A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms.

Antonini D, Sirico A, Aberdam E, Ambrosio R, Campanile C, Fagoonee S, Altruda F, Aberdam D, Brissette JL, Missero C.

Nucleic Acids Res. 2015 Jan;43(2):862-74. doi: 10.1093/nar/gku1396. Epub 2015 Jan 7.


Inactivation of p53 in Human Keratinocytes Leads to Squamous Differentiation and Shedding via Replication Stress and Mitotic Slippage.

Freije A, Molinuevo R, Ceballos L, Cagigas M, Alonso-Lecue P, Rodriguez R, Menendez P, Aberdam D, De Diego E, Gandarillas A.

Cell Rep. 2014 Nov 20;9(4):1349-60. doi: 10.1016/j.celrep.2014.10.012. Epub 2014 Nov 6.


Human embryonic stem cells prevent T-cell activation by suppressing dendritic cells function via TGF-beta signaling pathway.

Leshansky L, Aberdam D, Itskovitz-Eldor J, Berrih-Aknin S.

Stem Cells. 2014 Dec;32(12):3137-49. doi: 10.1002/stem.1833.


A mutation in TP63 causing a mild ectodermal dysplasia phenotype.

Goldsmith T, Eytan O, Magal L, Solomon M, Israeli S, Warshauer E, Grafi-Cohen M, Aberdam D, van Bokhoven H, Zhou H, Sarig O, Sprecher E, Nousbeck J.

J Invest Dermatol. 2014 Aug;134(8):2277-2280. doi: 10.1038/jid.2014.159. Epub 2014 Mar 27. No abstract available.


The 6th International p63/p73 Workshop: the C(ancer) and D(evelopmental) roles of p63 and p73.

Sabapathy K, Nagakawara A, Aberdam D.

Cell Death Differ. 2014 Aug;21(8):1340-2. doi: 10.1038/cdd.2013.192. Epub 2014 Jan 17. No abstract available.


Argonaute2 mediates compensatory expansion of the pancreatic β cell.

Tattikota SG, Rathjen T, McAnulty SJ, Wessels HH, Akerman I, van de Bunt M, Hausser J, Esguerra JL, Musahl A, Pandey AK, You X, Chen W, Herrera PL, Johnson PR, O'Carroll D, Eliasson L, Zavolan M, Gloyn AL, Ferrer J, Shalom-Feuerstein R, Aberdam D, Poy MN.

Cell Metab. 2014 Jan 7;19(1):122-34. doi: 10.1016/j.cmet.2013.11.015. Epub 2013 Dec 19.


Angiomodulin is required for cardiogenesis of embryonic stem cells and is maintained by a feedback loop network of p63 and Activin-A.

Wolchinsky Z, Shivtiel S, Kouwenhoven EN, Putin D, Sprecher E, Zhou H, Rouleau M, Aberdam D.

Stem Cell Res. 2014 Jan;12(1):49-59. doi: 10.1016/j.scr.2013.09.015. Epub 2013 Oct 6.


Abnormal neuronal differentiation and mitochondrial dysfunction in hair follicle-derived induced pluripotent stem cells of schizophrenia patients.

Robicsek O, Karry R, Petit I, Salman-Kesner N, Müller FJ, Klein E, Aberdam D, Ben-Shachar D.

Mol Psychiatry. 2013 Oct;18(10):1067-76. doi: 10.1038/mp.2013.67. Epub 2013 Jun 4.


Impaired epithelial differentiation of induced pluripotent stem cells from ectodermal dysplasia-related patients is rescued by the small compound APR-246/PRIMA-1MET.

Shalom-Feuerstein R, Serror L, Aberdam E, Müller FJ, van Bokhoven H, Wiman KG, Zhou H, Aberdam D, Petit I.

Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2152-6. doi: 10.1073/pnas.1201753109. Epub 2013 Jan 25.


A step closer toward therapies for p63-related disorders.

Zhou H, Aberdam D.

Rare Dis. 2013 Mar 12;1:e24247. doi: 10.4161/rdis.24247. eCollection 2013.

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