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Items: 14

1.

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma.

Ijichi H, Chytil A, Gorska AE, Aakre ME, Bierie B, Tada M, Mohri D, Miyabayashi K, Asaoka Y, Maeda S, Ikenoue T, Tateishi K, Wright CV, Koike K, Omata M, Moses HL.

J Clin Invest. 2011 Oct;121(10):4106-17. doi: 10.1172/JCI42754. Epub 2011 Sep 19.

2.

Disruption of bone morphogenetic protein receptor 2 (BMPR2) in mammary tumors promotes metastases through cell autonomous and paracrine mediators.

Owens P, Pickup MW, Novitskiy SV, Chytil A, Gorska AE, Aakre ME, West J, Moses HL.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2814-9. doi: 10.1073/pnas.1101139108. Epub 2011 May 16.

3.

Quantitative analysis of the secretome of TGF-beta signaling-deficient mammary fibroblasts.

Xu BJ, Yan W, Jovanovic B, An AQ, Cheng N, Aakre ME, Yi Y, Eng J, Link AJ, Moses HL.

Proteomics. 2010 Jul;10(13):2458-70. doi: 10.1002/pmic.200900701.

4.

Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells.

Bonine-Summers AR, Aakre ME, Brown KA, Arteaga CL, Pietenpol JA, Moses HL, Cheng N.

Cancer Biol Ther. 2007 Apr;6(4):561-70.

5.
6.

Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro.

Xie L, Law BK, Chytil AM, Brown KA, Aakre ME, Moses HL.

Neoplasia. 2004 Sep-Oct;6(5):603-10.

7.

Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro.

Brown KA, Aakre ME, Gorska AE, Price JO, Eltom SE, Pietenpol JA, Moses HL.

Breast Cancer Res. 2004;6(3):R215-31. Epub 2004 Mar 17.

8.

Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line.

Xie L, Law BK, Aakre ME, Edgerton M, Shyr Y, Bhowmick NA, Moses HL.

Breast Cancer Res. 2003;5(6):R187-98. Epub 2003 Aug 20.

10.

Transforming growth factor beta mimetics: discovery of 7-[4-(4-cyanophenyl)phenoxy]-heptanohydroxamic acid, a biaryl hydroxamate inhibitor of histone deacetylase.

Glaser KB, Li J, Aakre ME, Morgan DW, Sheppard G, Stewart KD, Pollock J, Lee P, O'Connor CZ, Anderson SN, Mussatto DJ, Wegner CW, Moses HL.

Mol Cancer Ther. 2002 Aug;1(10):759-68.

11.

Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells.

Law BK, Chytil A, Dumont N, Hamilton EG, Waltner-Law ME, Aakre ME, Covington C, Moses HL.

Mol Cell Biol. 2002 Dec;22(23):8184-98.

13.

Salicylate-induced growth arrest is associated with inhibition of p70s6k and down-regulation of c-myc, cyclin D1, cyclin A, and proliferating cell nuclear antigen.

Law BK, Waltner-Law ME, Entingh AJ, Chytil A, Aakre ME, Nørgaard P, Moses HL.

J Biol Chem. 2000 Dec 8;275(49):38261-7.

14.

Inhibition of cell growth by TGF beta 1 is associated with inhibition of B-myb and cyclin A in both BALB/MK and Mv1Lu cells.

Satterwhite DJ, Aakre ME, Gorska AE, Moses HL.

Cell Growth Differ. 1994 Aug;5(8):789-99.

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