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Items: 1 to 20 of 439

1.

Olaparib and ionizing radiation trigger a cooperative DNA-damage repair response that is impaired by depletion of the VRK1 chromatin kinase.

Campillo-Marcos I, Lazo PA.

J Exp Clin Cancer Res. 2019 May 17;38(1):203. doi: 10.1186/s13046-019-1204-1.

2.

Axitinib exposure triggers endothelial cells senescence through ROS accumulation and ATM activation.

Mongiardi MP, Radice G, Piras M, Stagni V, Pacioni S, Re A, Putti S, Ferrè F, Farsetti A, Pallini R, Barilà D, Levi A, Falchetti ML.

Oncogene. 2019 Apr 9. doi: 10.1038/s41388-019-0798-2. [Epub ahead of print]

PMID:
30967634
3.

Vitamin C increases DNA breaks and suppresses DNA damage-independent activation of ATM by bleomycin.

Rubis B, Luczak MW, Krawic C, Zhitkovich A.

Free Radic Biol Med. 2019 May 20;136:12-21. doi: 10.1016/j.freeradbiomed.2019.03.026. Epub 2019 Mar 26.

PMID:
30926564
4.

Time dependent response of daunorubicin on cytotoxicity, cell cycle and DNA repair in acute lymphoblastic leukaemia.

Al-Aamri HM, Ku H, Irving HR, Tucci J, Meehan-Andrews T, Bradley C.

BMC Cancer. 2019 Feb 27;19(1):179. doi: 10.1186/s12885-019-5377-y.

5.

Reduction of Gamma Radiation-Induced Damage by Hydro-Alcoholic Extract of Nardostachys jatamansi.

Menon A, Chacko T, Nair PR, Majeed T, Nair CKK.

J Environ Pathol Toxicol Oncol. 2019;38(1):83-96. doi: 10.1615/JEnvironPatholToxicolOncol.2019015395.

PMID:
30806293
6.

Microbial metabolites of proanthocyanidins reduce chemical carcinogen-induced DNA damage in human lung epithelial and fetal hepatic cells in vitro.

Thilakarathna WPDW, Rupasinghe HPV.

Food Chem Toxicol. 2019 Mar;125:479-493. doi: 10.1016/j.fct.2019.02.010. Epub 2019 Feb 5.

PMID:
30735747
7.

ATM orchestrates the DNA-damage response to counter toxic non-homologous end-joining at broken replication forks.

Balmus G, Pilger D, Coates J, Demir M, Sczaniecka-Clift M, Barros AC, Woods M, Fu B, Yang F, Chen E, Ostermaier M, Stankovic T, Ponstingl H, Herzog M, Yusa K, Martinez FM, Durant ST, Galanty Y, Beli P, Adams DJ, Bradley A, Metzakopian E, Forment JV, Jackson SP.

Nat Commun. 2019 Jan 8;10(1):87. doi: 10.1038/s41467-018-07729-2.

8.

DNA damage checkpoint response to aflatoxin B1.

Engin AB, Engin A.

Environ Toxicol Pharmacol. 2019 Jan;65:90-96. doi: 10.1016/j.etap.2018.12.006. Epub 2018 Dec 7. Review.

PMID:
30594067
9.

Adaptive responses to low doses of radiation or chemicals: their cellular and molecular mechanisms.

Guéguen Y, Bontemps A, Ebrahimian TG.

Cell Mol Life Sci. 2019 Apr;76(7):1255-1273. doi: 10.1007/s00018-018-2987-5. Epub 2018 Dec 8. Review.

PMID:
30535789
10.

Combination of chemotherapy and physical plasma elicits melanoma cell death via upregulation of SLC22A16.

Sagwal SK, Pasqual-Melo G, Bodnar Y, Gandhirajan RK, Bekeschus S.

Cell Death Dis. 2018 Dec 5;9(12):1179. doi: 10.1038/s41419-018-1221-6.

11.

Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice.

Hui CW, Song X, Ma F, Shen X, Herrup K.

J Neuroinflammation. 2018 Nov 6;15(1):308. doi: 10.1186/s12974-018-1338-7.

12.

Aromatic-turmerone ameliorates imiquimod-induced psoriasis-like inflammation of BALB/c mice.

Li YL, Du ZY, Li PH, Yan L, Zhou W, Tang YD, Liu GR, Fang YX, Zhang K, Dong CZ, Chen HX.

Int Immunopharmacol. 2018 Nov;64:319-325. doi: 10.1016/j.intimp.2018.09.015. Epub 2018 Sep 19.

PMID:
30243067
13.

Rotundic acid enhances the impact of radiological toxicity on MCF-7 cells through the ATM/p53 pathway.

Wang ZF, Sun WY, Yu DH, Zhao Y, Xu HM, He YF, Li HJ.

Int J Oncol. 2018 Nov;53(5):2269-2277. doi: 10.3892/ijo.2018.4544. Epub 2018 Aug 29.

PMID:
30226600
14.

Discovery and Characterization of 4-Hydroxy-2-pyridone Derivative Sambutoxin as a Potent and Promising Anticancer Drug Candidate: Activity and Molecular Mechanism.

Li LN, Wang L, Cheng YN, Cao ZQ, Zhang XK, Guo XL.

Mol Pharm. 2018 Nov 5;15(11):4898-4911. doi: 10.1021/acs.molpharmaceut.8b00525. Epub 2018 Sep 28.

PMID:
30223653
15.

New Bis copper complex ((Z) -4 - ((4-chlorophenyl) amino) -4-oxobut-2-enoyl) oxy): Cytotoxicity in 4T1 cells and their toxicogenic potential in Swiss mice.

de Oliveira EJT, Pessatto LR, de Freitas RON, Pelizaro BI, Rabacow APM, Vani JM, Monreal ACD, Mantovani MS, de Azevedo RB, Antoniolli-Silva ACMB, da Silva Gomes R, Oliveira RJ.

Toxicol Appl Pharmacol. 2018 Oct 1;356:127-138. doi: 10.1016/j.taap.2018.08.004. Epub 2018 Aug 6.

PMID:
30092250
16.

Formulation of Natural Oil Nano-Emulsions for the Topical Delivery of Clofazimine, Artemisone and Decoquinate.

Burger C, Aucamp M, du Preez J, Haynes RK, Ngwane A, du Plessis J, Gerber M.

Pharm Res. 2018 Aug 7;35(10):186. doi: 10.1007/s11095-018-2471-9.

PMID:
30088097
17.

Influence of PARP-1 inhibition in the cardiotoxicity of the topoisomerase 2 inhibitors doxorubicin and mitoxantrone.

Damiani RM, Moura DJ, Viau CM, Brito V, Morás AM, Henriques JAP, Saffi J.

Toxicol In Vitro. 2018 Oct;52:203-213. doi: 10.1016/j.tiv.2018.06.013. Epub 2018 Jun 15.

PMID:
29913208
18.

Financial toxicity and implications for cancer care in the era of molecular and immune therapies.

Tran G, Zafar SY.

Ann Transl Med. 2018 May;6(9):166. doi: 10.21037/atm.2018.03.28. Review.

19.

Rational Design of Cancer-Targeted Selenadiazole Derivative as Efficient Radiosensitizer for Precise Cancer Therapy.

Zeng D, Deng S, Sang C, Zhao J, Chen T.

Bioconjug Chem. 2018 Jun 20;29(6):2039-2049. doi: 10.1021/acs.bioconjchem.8b00247. Epub 2018 May 29.

PMID:
29771500
20.

Immune checkpoint pathways in non-small cell lung cancer.

Chae YK, Arya A, Iams W, Cruz M, Mohindra N, Villaflor V, Giles FJ.

Ann Transl Med. 2018 Mar;6(5):88. doi: 10.21037/atm.2017.09.30. Review.

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