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See Gene information for atm chek1

atm in Homo sapiens (2)Mus musculus (2)Rattus norvegicus (2)All 274 Gene records

chek1 in Homo sapiens (2)Mus musculus (2)Rattus norvegicus (2)All 260 Gene records

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Items: 1 to 20 of 385


Targeting Topoisomerase I in the Era of Precision Medicine.

Thomas A, Pommier Y.

Clin Cancer Res. 2019 Jun 21. pii: clincanres.1089.2019. doi: 10.1158/1078-0432.CCR-19-1089. [Epub ahead of print]


Targeting the cell cycle in head and neck cancer by Chk1 inhibition: a novel concept of bimodal cell death.

van Harten AM, Buijze M, van der Mast R, Rooimans MA, Martens-de Kemp SR, Bachas C, Brink A, Stigter-van Walsum M, Wolthuis RMF, Brakenhoff RH.

Oncogenesis. 2019 Jun 17;8(7):38. doi: 10.1038/s41389-019-0147-x.


Analysis of DNA Damage Response Gene Alterations and Tumor Mutational Burden Across 17,486 Tubular Gastrointestinal Carcinomas: Implications for Therapy.

Parikh AR, He Y, Hong TS, Corcoran RB, Clark JW, Ryan DP, Zou L, Ting DT, Catenacci DV, Chao J, Fakih M, Klempner SJ, Ross JS, Frampton GM, Miller VA, Ali SM, Schrock AB.

Oncologist. 2019 Apr 30. pii: theoncologist.2019-0034. doi: 10.1634/theoncologist.2019-0034. [Epub ahead of print]


Analysis of the cytotoxic, genotoxic, mutagenic, and pro-oxidant effect of synephrine, a component of thermogenic supplements, in human hepatic cells in vitro.

Ribeiro DL, Machado ART, da Silva Machado C, Santos PWDS, Aissa AF, Barcelos GRM, Antunes LMG.

Toxicology. 2019 Jun 15;422:25-34. doi: 10.1016/j.tox.2019.04.010. Epub 2019 Apr 17.


Kinase-dead ATR differs from ATR loss by limiting the dynamic exchange of ATR and RPA.

Menolfi D, Jiang W, Lee BJ, Moiseeva T, Shao Z, Estes V, Frattini MG, Bakkenist CJ, Zha S.

Nat Commun. 2018 Dec 17;9(1):5351. doi: 10.1038/s41467-018-07798-3.


Resveratrol analog, N-(4-methoxyphenyl)-3,5-dimethoxybenzamide induces G2/M phase cell cycle arrest and apoptosis in HeLa human cervical cancer cells.

Lee KW, Chung KS, Lee JH, Choi JH, Choi SY, Kim S, Lee JY, Lee KT.

Food Chem Toxicol. 2019 Feb;124:101-111. doi: 10.1016/j.fct.2018.11.062. Epub 2018 Nov 30.


Prevalence of Homologous Recombination-Related Gene Mutations Across Multiple Cancer Types.

Heeke AL, Pishvaian MJ, Lynce F, Xiu J, Brody JR, Chen WJ, Baker TM, Marshall JL, Isaacs C.

JCO Precis Oncol. 2018;2018. doi: 10.1200/PO.17.00286. Epub 2018 Jul 23.


Prevalence of DNA repair gene mutations in localized prostate cancer according to clinical and pathologic features: association of Gleason score and tumor stage.

Marshall CH, Fu W, Wang H, Baras AS, Lotan TL, Antonarakis ES.

Prostate Cancer Prostatic Dis. 2019 Mar;22(1):59-65. doi: 10.1038/s41391-018-0086-1. Epub 2018 Aug 31.


Transient inhibition of p53 homologs protects ovarian function from two distinct apoptotic pathways triggered by anticancer therapies.

Kim SY, Nair DM, Romero M, Serna VA, Koleske AJ, Woodruff TK, Kurita T.

Cell Death Differ. 2019 Mar;26(3):502-515. doi: 10.1038/s41418-018-0151-2. Epub 2018 Jul 9.


Association of genetic variants in ATR-CHEK1 and ATM-CHEK2 pathway genes with risk of colorectal cancer in a Chinese population.

Wang S, Zhang Y, Chen M, Wang Y, Feng Y, Xu Z, Zhang D, Sun Y, Fu Z.

Oncotarget. 2018 Jan 23;9(42):26616-26624. doi: 10.18632/oncotarget.24299. eCollection 2018 Jun 1.


Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer.

Kondo T, Kanai M, Kou T, Sakuma T, Mochizuki H, Kamada M, Nakatsui M, Uza N, Kodama Y, Masui T, Takaori K, Matsumoto S, Miyake H, Okuno Y, Muto M.

Oncotarget. 2018 Apr 13;9(28):19817-19825. doi: 10.18632/oncotarget.24865. eCollection 2018 Apr 13.


Genomic instability in adult men involved in processing electronic waste in Northern China.

Wang Y, Sun X, Fang L, Li K, Yang P, Du L, Ji K, Wang J, Liu Q, Xu C, Li G, Giesy JP, Hecker M.

Environ Int. 2018 Aug;117:69-81. doi: 10.1016/j.envint.2018.04.027. Epub 2018 May 1.


HDAC1 and HDAC2 integrate checkpoint kinase phosphorylation and cell fate through the phosphatase-2A subunit PR130.

Göder A, Emmerich C, Nikolova T, Kiweler N, Schreiber M, Kühl T, Imhof D, Christmann M, Heinzel T, Schneider G, Krämer OH.

Nat Commun. 2018 Feb 22;9(1):764. doi: 10.1038/s41467-018-03096-0.


Radiation-induced G2/M arrest rarely occurred in glioblastoma stem-like cells.

Liu J, Liu Y, Xie T, Luo L, Xu C, Gao Q, Shen L, Wan F, Lei T, Ye F.

Int J Radiat Biol. 2018 Apr;94(4):394-402. doi: 10.1080/09553002.2018.1440094. Epub 2018 Feb 27.


CHEK1 coordinates DNA damage signaling and meiotic progression in the male germline of mice.

Abe H, Alavattam KG, Kato Y, Castrillon DH, Pang Q, Andreassen PR, Namekawa SH.

Hum Mol Genet. 2018 Apr 1;27(7):1136-1149. doi: 10.1093/hmg/ddy022.


Chk1 activation attenuates sensitivity of lapatinib in HER2-positive gastric cancer.

Bai M, Song N, Che X, Wang X, Qu X, Liu Y.

Cell Biol Int. 2018 Jul;42(7):781-793. doi: 10.1002/cbin.10922. Epub 2018 May 14.


The ATM and Rad3-Related (ATR) Protein Kinase Pathway Is Activated by Herpes Simplex Virus 1 and Required for Efficient Viral Replication.

Edwards TG, Bloom DC, Fisher C.

J Virol. 2018 Feb 26;92(6). pii: e01884-17. doi: 10.1128/JVI.01884-17. Print 2018 Mar 15.


DNA damage causes rapid accumulation of phosphoinositides for ATR signaling.

Wang YH, Hariharan A, Bastianello G, Toyama Y, Shivashankar GV, Foiani M, Sheetz MP.

Nat Commun. 2017 Dec 14;8(1):2118. doi: 10.1038/s41467-017-01805-9.


Current status of poly(ADP-ribose) polymerase inhibitors and future directions.

Ohmoto A, Yachida S.

Onco Targets Ther. 2017 Oct 26;10:5195-5208. doi: 10.2147/OTT.S139336. eCollection 2017. Review.


Candidate synthetic lethality partners to PARP inhibitors in the treatment of ovarian clear cell cancer.

Kawahara N, Ogawa K, Nagayasu M, Kimura M, Sasaki Y, Kobayashi H.

Biomed Rep. 2017 Nov;7(5):391-399. doi: 10.3892/br.2017.990. Epub 2017 Sep 27.

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