Send to

Choose Destination
See comment in PubMed Commons below
Ann N Y Acad Sci. 1998 Nov 30;855:205-7.

Visualizing odor detection in olfactory cilia by calcium imaging.

Author information

Section of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.


To visualize odor detection in individual cilia of olfactory sensory neurons we have developed a new approach by using high-resolution calcium imaging techniques. Laser scanning confocal microscopy revealed, for the first time, that odor stimuli induce transient Ca2+ elevations in single olfactory cilia. Pharmacological analysis indicates that these Ca2+ signals depend entirely on Ca2+ entry through activated cyclic nucleotide-gated (CNG) channels. This novel approach enables us to monitor the initial steps leading to olfactory perception in a spatially and temporally resolved manner.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Wiley
    Loading ...
    Support Center