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J Cancer Res Clin Oncol. 1996;122(9):566-7.

Mediastinal infusion of epirubicin and 5-fluorouracil. A complication of totally implantable central venous systems. Report of a case.

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1
Department of Internal Medicine-Oncology, Hotel-Dieu, Paris, France.

Abstract

Perforation of the wall of the superior vena cava by a central venous catheter is reported. The resultant inadvertent infusion of 5-fluorouracil and epirubicin caused a severe acute inflammatory reaction in the right-lobe bronchus, mediastinal infiltration and pleural and pericardial effusions. The patient recovered but has residual mild oesophageal dysfunction.

PMID:
8781572
[Indexed for MEDLINE]
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