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Magn Reson Med. 1993 Sep;30(3):347-50.

In vivo 31P NMR measurement of glucose-6-phosphate in the rat muscle after exercise.

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Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510.


Comparison of 31P NMR spectra of the rat gastrocnemius, obtained in vivo and from PCA extracts, after electrically induced contractions, demonstrates that glucose-6-phosphate (G6P) is the major metabolite in the low-field part of the PME spectral region. In vivo 31P NMR can thus be used to measure the muscle G6P concentration after exercise.

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