Format

Send to

Choose Destination
J Med Genet. 1993 Jun;30(6):501-2.

Frequency of delta F508 in a Mexican sample of cystic fibrosis patients.

Author information

1
Human Genetics Department, Instituto Nacional de Pediatría, Mexico, DF.

Abstract

This paper reports the frequency of the delta F508 mutation in a cohort of 50 Mexican patients with cystic fibrosis (CF). The mutation was detected by PCR mediated site directed mutagenesis. delta F508 was found in 39% of CF chromosomes, a frequency lower than that reported in Argentina and Spain. The high rate of CF cases who die undiagnosed, the ethnic origin of Mexican populations, and the limited number of cases studied could account for the low frequency of the delta F508 mutation found in this preliminary report.

PMID:
8326494
PMCID:
PMC1016425
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for HighWire Icon for PubMed Central
Loading ...
Support Center