Format

Send to

Choose Destination
See comment in PubMed Commons below
Antimicrob Agents Chemother. 1994 Sep;38(9):2175-9.

Substrate specificity of Epstein-Barr virus thymidine kinase.

Author information

1
Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, Connecticut 06520-8040.

Abstract

Purified recombinant protein encoded by the BXLF-I open reading frame of the Epstein-Barr virus genome has thymidine kinase activity. The substrate behaviors of various nucleosides toward this enzyme were tested. Halogenated deoxyuridines, zidovudine, and bromovinyldeoxyuridine are efficient substrates, while acyclovir and dihydroxypropylmethylguanine are relatively poor substrates for the Epstein-Barr virus thymidine kinase.

PMID:
7811040
PMCID:
PMC284705
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center