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J Clin Psychiatry. 1983 May;44(5 Pt 2):134-6.

Safety and efficacy of bupropion in elderly patients: preliminary observations.


The efficacy and safety of bupropion, an atypical antidepressant, were assessed in depressed patients aged 55 and above. Data were analyzed for 38 patients who completed 4 weeks of double-blind treatment with bupropion in maximum doses of 150 or 450 mg/day; imipramine, up to 200 mg/day; or placebo. Preliminary results suggest that bupropion does have antidepressant activity and is well tolerated in this population. A particular advantage is suggested in terms of cardiovascular side effects.

[Indexed for MEDLINE]

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