Format

Send to

Choose Destination
J Hepatol. 2015 Oct;63(4):838-47. doi: 10.1016/j.jhep.2015.05.003. Epub 2015 May 20.

Informed consent for live liver donors: A qualitative, prospective study.

Author information

1
Center for Healthcare Studies, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States; Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States. Electronic address: e-gordon@northwestern.edu.
2
Center for Healthcare Studies, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.
3
Comprehensive Transplant Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States.

Abstract

BACKGROUND & AIMS:

Adult-to-adult live donor liver transplantation (LDLT) poses serious health risks and no direct health benefits to donors. Ensuring live donors' autonomy through informed consent is critical. We assessed live liver donors' (LD) comprehension, information needs, risk perceptions, and demographics.

METHODS:

Semi-structured interviews were prospectively conducted with LDs after completing donor evaluation and informed consent at our transplant center. Likert scales measured informed consent domains. Open-ended responses underwent thematic analysis.

RESULTS:

Thirty LDs participated (100% participation rate). Although 90% of LDs reported being informed about donation 'a great deal', only 66% reported understanding information about donation 'a great deal.' Many (40%) reported difficulty understanding medical terminology. Information LDs most desired to feel comfortable with their decision included: incidence and type of donor complications (67%), description of donation procedure (57%), and the process of donor preparation (43%). Most (83%) LDs rated risks to themselves as 'not at all' to 'somewhat' risky, and minimized these risks.

CONCLUSIONS:

Although LDs perceived that they were adequately informed, their actual comprehension about donation was inadequate. Findings suggest the value of informed consent for preparation for the procedure and potential periprocedural risks rather than for decision-making. More comprehensible information disclosure may optimize informed consent.

KEYWORDS:

Bioethics; Education; Information needs; Informed consent; Liver transplantation; Qualitative research; Risk communication

PMID:
26003265
DOI:
10.1016/j.jhep.2015.05.003
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center