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1.

PET Imaging of 18F-FDG, 11C-methionine, 11C-flumazenil, and 11C-4DST in Progressive Multifocal Leukoencephalopathy.

Ishibashi K, Miura Y, Matsumura K, Kanemasa Y, Nakamichi K, Saijo M, Toyohara J, Ishii K.

Intern Med. 2017;56(10):1219-1223. doi: 10.2169/internalmedicine.56.8080. Epub 2017 May 15.

2.

Introduction of nuclear medicine research in Japan.

Inubushi M, Higashi T, Kuji I, Sakamoto S, Tashiro M, Momose M.

Eur J Nucl Med Mol Imaging. 2016 Dec;43(13):2449-2452. Epub 2016 Aug 4.

3.

Evaluation of DNA synthesis with carbon-11-labeled 4'-thiothymidine.

Toyohara J.

World J Radiol. 2016 Sep 28;8(9):799-808. Review.

4.

Influence of volumetric 4'-[methyl-11C]-thiothymidine PET/CT parameters for prediction of the clinical outcome of head and neck cancer patients.

Hoshikawa H, Mori T, Maeda Y, Takahashi S, Ouchi Y, Yamamoto Y, Nishiyama Y.

Ann Nucl Med. 2017 Jan;31(1):63-70. doi: 10.1007/s12149-016-1131-6. Epub 2016 Sep 27.

PMID:
27679399
5.

Rose Bengal-photosensitized oxidation of 4-thiothymidine in aqueous medium: evidence for the reaction of the nucleoside with singlet state oxygen.

Rizzi V, Losito I, Ventrella A, Fini P, Fraix A, Sortino S, Agostiano A, Longobardi F, Cosma P.

Phys Chem Chem Phys. 2015 Oct 21;17(39):26307-19. doi: 10.1039/c5cp03615a.

PMID:
26387532
6.

Comparison of 4'-[methyl-(11)C]thiothymidine ((11)C-4DST) and 3'-deoxy-3'-[(18)F]fluorothymidine ((18)F-FLT) PET/CT in human brain glioma imaging.

Toyota Y, Miyake K, Kawai N, Hatakeyama T, Yamamoto Y, Toyohara J, Nishiyama Y, Tamiya T.

EJNMMI Res. 2015 Mar 5;5:7. doi: 10.1186/s13550-015-0085-3. eCollection 2015.

7.

In vitro analysis of transport and metabolism of 4'-thiothymidine in human tumor cells.

Plotnik DA, Wu S, Linn GR, Yip FC, Comandante NL, Krohn KA, Toyohara J, Schwartz JL.

Nucl Med Biol. 2015 May;42(5):470-4. doi: 10.1016/j.nucmedbio.2014.12.005. Epub 2014 Dec 6.

8.

Comparison of (11)C-4'-thiothymidine, (11)C-methionine, and (18)F-FDG PET/CT for the detection of active lesions of multiple myeloma.

Okasaki M, Kubota K, Minamimoto R, Miyata Y, Morooka M, Ito K, Ishiwata K, Toyohara J, Inoue T, Hirai R, Hagiwara S, Miwa A.

Ann Nucl Med. 2015 Apr;29(3):224-32. doi: 10.1007/s12149-014-0931-9. Epub 2014 Nov 25.

9.

Volumetric comparison of positron emission tomography/computed tomography using 4'-[methyl-¹¹C]-thiothymidine with 2-deoxy-2-¹⁸F-fluoro-D-glucose in patients with advanced head and neck squamous cell carcinoma.

Ito K, Yokoyama J, Miyata Y, Toyohara J, Okasaki M, Minamimoto R, Morooka M, Ishiwata K, Kubota K.

Nucl Med Commun. 2015 Mar;36(3):219-25. doi: 10.1097/MNM.0000000000000241.

PMID:
25369751
10.

Efficient syntheses of [¹¹C]zidovudine and its analogs by convenient one-pot palladium(0)-copper(I) co-mediated rapid C-[¹¹C]methylation.

Zhang Z, Doi H, Koyama H, Watanabe Y, Suzuki M.

J Labelled Comp Radiopharm. 2014 Jun 30;57(8):540-9. doi: 10.1002/jlcr.3213. Epub 2014 Jul 3.

PMID:
24992010
11.

Antiherpesvirus activities of two novel 4'-thiothymidine derivatives, KAY-2-41 and KAH-39-149, are dependent on viral and cellular thymidine kinases.

Coen N, Duraffour S, Haraguchi K, Balzarini J, van den Oord JJ, Snoeck R, Andrei G.

Antimicrob Agents Chemother. 2014 Aug;58(8):4328-40. doi: 10.1128/AAC.02825-14. Epub 2014 May 12.

12.

KAY-2-41, a novel nucleoside analogue inhibitor of orthopoxviruses in vitro and in vivo.

Duraffour S, Drillien R, Haraguchi K, Balzarini J, Topalis D, van den Oord JJ, Andrei G, Snoeck R.

Antimicrob Agents Chemother. 2014;58(1):27-37. doi: 10.1128/AAC.01601-13. Epub 2013 Oct 14.

13.

Methyl-[<sup>11</sup>C]-4'-thiothymidine.

Chopra A.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2011 Aug 1 [updated 2011 Sep 8].

14.

Whole-body distribution and brain tumor imaging with (11)C-4DST: a pilot study.

Toyohara J, Nariai T, Sakata M, Oda K, Ishii K, Kawabe T, Irie T, Saga T, Kubota K, Ishiwata K.

J Nucl Med. 2011 Aug;52(8):1322-8. doi: 10.2967/jnumed.111.088435. Epub 2011 Jul 15.

15.

Highly efficient syntheses of [methyl-11C]thymidine and its analogue 4'-[methyl-11C]thiothymidine as nucleoside PET probes for cancer cell proliferation by Pd(0)-mediated rapid C-[11C]methylation.

Koyama H, Siqin, Zhang Z, Sumi K, Hatta Y, Nagata H, Doi H, Suzuki M.

Org Biomol Chem. 2011 Jun 7;9(11):4287-94. doi: 10.1039/c0ob01249a. Epub 2011 Apr 18.

PMID:
21503302
16.

Synthesis and anti-HIV activity of 4'-substituted 4'-thiothymidines: a new entry based on nucleophilic substitution of the 4'-acetoxy group.

Haraguchi K, Shimada H, Tanaka H, Hamasaki T, Baba M, Gullen EA, Dutschman GE, Cheng YC.

J Med Chem. 2008 Mar 27;51(6):1885-93. doi: 10.1021/jm070824s. Epub 2008 Feb 27. Erratum in: J Med Chem. 2008 Aug 14;51(15):4850.

PMID:
18311897
17.

Feasibility studies of 4'-[methyl-(11)C]thiothymidine as a tumor proliferation imaging agent in mice.

Toyohara J, Okada M, Toramatsu C, Suzuki K, Irie T.

Nucl Med Biol. 2008 Jan;35(1):67-74.

PMID:
18158945
18.

Nucleophilic substitution of 4'-acetoxy-4'-thionucleosides: a new access to 4'-substituted 4'-thiothymidines.

Haraguchi K, Shimada H, Tanaka H.

Nucleic Acids Symp Ser (Oxf). 2006;(50):115-6.

PMID:
17150844
19.

Evaluation of 4'-[methyl-14C]thiothymidine for in vivo DNA synthesis imaging.

Toyohara J, Kumata K, Fukushi K, Irie T, Suzuki K.

J Nucl Med. 2006 Oct;47(10):1717-22.

20.

Practical synthesis of 2'-deoxy-4'-thioribonucleosides: substrates for the synthesis of 4'-thioDNA.

Inoue N, Kaga D, Minakawa N, Matsuda A.

J Org Chem. 2005 Oct 14;70(21):8597-600.

PMID:
16209618

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