Format

Send to

Choose Destination
Arch Dermatol Res. 2020 Mar;312(2):103-111. doi: 10.1007/s00403-019-01998-7. Epub 2019 Oct 15.

Pruritus and sleep disturbances in patients with psoriasis.

Author information

1
Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany.
2
Psychodermatology Department, Clinical Immunology and Rheumatology, Medical University of Łódź, Łódź, Poland.
3
Department of Dermatology and Allergy, Charité-Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Germany. marcus.maurer@charite.de.

Abstract

Psoriasis is a prevalent skin disease that impairs multiple domains of quality of life (QoL). Pruritus, a common symptom in patients with psoriasis, may directly affect sleep, but studies investigating this are limited. We investigated the relationships between pruritus and sleep in 104 in-patients with psoriasis, who underwent dermatological assessment and completed questionnaires to determine psoriasis severity, pruritus intensity, sleep quality, QoL (skin disease-specific and generic), depressive mood and anxiety. In total, 80% of patients reported pruritus, and 39% had sleep disturbances, most commonly awakenings during sleep (33%) and sleepiness during the daytime (30%). Sleep impairment was more frequent in patients with pruritus, who had more difficulty falling asleep (P = 0.031). Overall, 14% of all patients and 34% of the patients who reported sleep disturbances reported that their sleep problems were caused by pruritus. Patients who reported sleep disturbances had lower generic QoL. Pruritus in patients with psoriasis was frequent and relevant, as evidenced by the higher rate of sleep problems in this patient group, and it was linked to a lower QoL.

KEYWORDS:

Anxiety; Depression; Pruritus; Psoriasis; Quality of life; Sleep

PMID:
31616971
DOI:
10.1007/s00403-019-01998-7

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center