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Medicine (Baltimore). 2019 Apr;98(16):e15301. doi: 10.1097/MD.0000000000015301.

Depression involved in self-reported prospective memory problems in survivors of breast cancer who have received chemotherapy.

Author information

1
Department of Oncology, The Second Affiliated Hospital of Anhui Medical University.
2
Department of Oncology, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui.
3
Cancer Center, VA Connecticut Healthcare System, West Haven.
4
Department of Internal Medicine, Yale University School of Medicine.
5
Department of Psychiatry, Yale University School of Medicine, New Haven, CT.

Abstract

To investigate the relationship between depression and the self-reported prospective memory (SPM) problems in breast cancer survivors who have received chemotherapy.Sixty-three breast cancer patients were administered with self-rating depression scale (SDS) and the prospective memory questionnaire as part of extensive neuropsychological assessments before and after chemotherapy. The performance of SDS and SPM were compared, with the level of significance set at P < .05.Compared with the group before chemotherapy, there is a significant difference on the SPM score (t = 6.069, P = .000) in breast cancer patients after chemotherapy. Further, there is also a significant difference on the SPM score (t = -4.348, P = .000) between the patients with and without depression group after chemotherapy.The present result indicated that the depression in breast cancer survivors after chemotherapy may be involved in their chemotherapy-induced SPM impairment.

PMID:
31008981
PMCID:
PMC6494378
DOI:
10.1097/MD.0000000000015301
[Indexed for MEDLINE]
Free PMC Article

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