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Immunity. 2018 Oct 16;49(4):579-582. doi: 10.1016/j.immuni.2018.10.002.

Cenabis Bene: Treg Cells Invite Macrophages to Dine.

Author information

1
Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06510, USA.
2
Department of Neurology, School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06510, USA. Electronic address: sourav.ghosh@yale.edu.
3
Department of Immunobiology, School of Medicine, Yale University, New Haven, CT 06510, USA; Department of Pharmacology, School of Medicine, Yale University, New Haven, CT 06510, USA. Electronic address: carla.rothlin@yale.edu.

Abstract

Resolution of the immune response requires a coordinated effort to dampen inflammatory mediators and remove dying cells and debris. In this issue of Immunity, Proto et al. (2018) describe a circuit by which regulatory T cells enhance macrophage consumption of apoptotic cells during resolution.

PMID:
30332622
DOI:
10.1016/j.immuni.2018.10.002
[Indexed for MEDLINE]

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