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Curr Biol. 2018 Sep 24;28(18):R1117-R1119. doi: 10.1016/j.cub.2018.08.019.

Gut Microbiota: IgA Protects the Pioneers.

Author information

1
Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: whitman.schofield@yale.edu.
2
Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: noah.palm@yale.edu.

Abstract

The secretory antibody immunoglobulin A counteracts pathogenic infections at mucosal surfaces. Recent work now reveals that IgA responses can also stabilize intestinal colonization by symbiotic microorganisms and confer resistance to future invasion by exogenous competitors.

PMID:
30253156
DOI:
10.1016/j.cub.2018.08.019

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