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Vet Clin North Am Small Anim Pract. 2019 Jan;49(1):1-7. doi: 10.1016/j.cvsm.2018.08.001. Epub 2018 Sep 15.

Update on Allergen Immunotherapy.

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Centre for Clinical Veterinary Medicine, Medizinische Kleintierklinik, LMU Munich, Veterinaerstr. 13, Munich 80539, Bavaria, Germany. Electronic address:


Allergen immunotherapy has been used for many years in dogs and cats and is the only specific treatment of atopic dermatitis that changes the patho-mechanisms of disease by stimulating allergen tolerance. Subcutaneous administration of allergens is the most commonly used administration route, typically in increasing concentrations (induction period) followed by long-term injection of allergen extract (maintenance therapy). Rush protocols with an abbreviated induction period have been reported and shown to be safe in dogs. More recently, oro-mucosal and intralymphatic administration of allergens has been evaluated in dogs. Approximately two-thirds of patients show good to excellent improvement of clinical signs.


Allergen specific; Canine; Desensitization; Feline; Hyposensitization; Intralymphatic


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