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Curr Biol. 2018 Jun 18;28(12):R702-R704. doi: 10.1016/j.cub.2018.05.041.

Transgenerational Inheritance: Parental Guidance Suggested.

Author information

1
Biology Department, Washington University in St. Louis, One Brookings Drive, St. Louis, MO 63130, USA. Electronic address: dchalker@wustl.edu.

Abstract

RNAs have been attractive candidates to transmit epigenetic information over multiple generations. In Tetrahymena, a new study demonstrates that the selective degradation of small RNAs that occurs by interaction with the parental genome can communicate altered patterns of heterochromatin formation and DNA elimination in offspring.

PMID:
29920263
DOI:
10.1016/j.cub.2018.05.041

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