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Cureus. 2018 Mar 22;10(3):e2358. doi: 10.7759/cureus.2358.

Long-term Quality of Life in Survivors of Brain Metastases: A Roller Coaster of Perspective.

Author information

1
Department of Medicine, Frank H. Netter Md School of Medicine.
2
Neurology, Yale School of Medicine.
3
Medicine, Frank H. Netter Md School of Medicine.
4
Radiation Oncology, Yale School of Medicine.
5
Department of Neurosurgery, Yale School of Medicine.
6
Neurosurgery, Yale School of Medicine.

Abstract

Longevity in cancer patients with brain metastases is increasingly being observed. This raises discussions about how best to maintain a good quality of life for these patients. Recent data suggest that post-treatment quality of life (QoL) can be maintained using new treatment options, but little data exist regarding the QoL in long-term survivors. This study of 19 patients surviving greater than two years from the initial treatment of brain metastases suggests that long-term QoL can be better than at the start of treatment and perhaps even better than normal, especially between three and five years post-treatment. This improved QoL seems mostly attributable to improved functional and social well-being and is possible as long as emotional and physical well-being are maintained within the normal range.

KEYWORDS:

brain metastasis; breast cancer survivors; gamma knife radiosurgery; long-term toxicity; quality of life; radiation oncology; stereotactic radiosurgery

Conflict of interest statement

The authors have declared that no competing interests exist.

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