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Cell Metab. 2017 Dec 5;26(6):813-815. doi: 10.1016/j.cmet.2017.11.007.

MAIT Cells: A Link between Gut Integrity and Type 1 Diabetes.

Author information

1
Department of Immunobiology, Yale University, New Haven, CT 06520, USA.
2
Department of Immunobiology, Yale University, New Haven, CT 06520, USA. Electronic address: kevan.herold@yale.edu.

Abstract

Type 1 diabetes (T1D) is a multifactorial autoimmune disease whose etiology involves complex interactions between the immune system and the intestinal microbiota. Recent studies by Rouxel et al. (2017) suggest that innate-like mucosal-associated invariant T cells (MAIT cells) may link gut integrity, the microbiota, and T1D.

PMID:
29211981
DOI:
10.1016/j.cmet.2017.11.007
[Indexed for MEDLINE]
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