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Dev Cell. 2017 Jun 5;41(5):455-456. doi: 10.1016/j.devcel.2017.05.020.

Tregs Expand the Skin Stem Cell Niche.

Author information

1
Departments of Molecular, Cellular and Developmental Biology and Dermatology, Yale University, New Haven, CT 06520, USA. Electronic address: valerie.horsley@yale.edu.
2
Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY 10065, USA.

Abstract

Regulatory T cells (Tregs) are emerging as an essential stem cell niche component that promotes wound repair in adipose, muscle, and lung tissues. Recently in Cell, Ali et al. (2017) report that skin resident Tregs facilitate the proliferation and differentiation of hair follicle stem cells through Notch signaling.

PMID:
28586641
DOI:
10.1016/j.devcel.2017.05.020
[Indexed for MEDLINE]
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