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Int J Mol Sci. 2017 Apr 24;18(4). pii: E898. doi: 10.3390/ijms18040898.

Glyoxalase Goes Green: The Expanding Roles of Glyoxalase in Plants.

Author information

1
Department of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, Canada. subbu@itbm.nagoya-u.ac.jp.
2
Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8602, Japan. subbu@itbm.nagoya-u.ac.jp.
3
Department of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, Canada. mjamshed@ucalgary.ca.
4
Department of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, Canada. abhinandan.kumar2@ucalgary.ca.
5
Department of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, Canada. laskori@ucalgary.ca.
6
Department of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, Canada. sscandol@ucalgary.ca.
7
Department of Chemistry, Yale University, 225 Prospect St., New Haven, CT 06511, USA. tina.wang@yale.edu.
8
Department of Chemistry, Yale University, 225 Prospect St., New Haven, CT 06511, USA. david.spiegel@yale.edu.
9
Department of Biological Sciences, University of Calgary, Calgary AB T2N 1N4, Canada. msamuel@ucalgary.ca.

Abstract

The ubiquitous glyoxalase enzymatic pathway is involved in the detoxification of methylglyoxal (MG), a cytotoxic byproduct of glycolysis. The glyoxalase system has been more extensively studied in animals versus plants. Plant glyoxalases have been primarily associated with stress responses and their overexpression is known to impart tolerance to various abiotic stresses. In plants, glyoxalases exist as multigene families, and new roles for glyoxalases in various developmental and signaling pathways have started to emerge. Glyoxalase-based MG detoxification has now been shown to be important for pollination responses. During self-incompatibility response in Brassicaceae, MG is required to target compatibility factors for proteasomal degradation, while accumulation of glyoxalase leads to MG detoxification and efficient pollination. In this review, we discuss the importance of glyoxalase systems and their emerging biological roles in plants.

KEYWORDS:

development; glyoxalase; methylglyoxal; plants; stress response

PMID:
28441779
PMCID:
PMC5412477
DOI:
10.3390/ijms18040898
[Indexed for MEDLINE]
Free PMC Article

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