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Aging (Albany NY). 2017 Jan 29;9(1):7-25. doi: 10.18632/aging.101163.

A review of the biomedical innovations for healthy longevity.

Author information

1
Moscow Institute of Physics and Technology, Dolgoprudny, 141700, Russia.
2
Institute of Biology of Komi Science Center of Ural Branch of Russian Academy of Sciences, Syktyvkar, 167982, Russia.
3
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
4
Vavilov Institute of General Genetics RAS, Moscow, Russia.
5
Department of Carcinogenesis and Oncogerontology, N.N. Petrov Research Institute of Oncology, St. Petersburg, Russia.
6
Pharmaceutical Artificial Intelligence Department, Insilico Medicine, ETC, B301, Johns Hopkins University, Baltimore, Maryland 21218, USA.
7
Bayer Global Drug Discovery, Berlin, Germany.
8
Social Science Research Institute, Duke University, Durham, NC 27708, USA.
9
School of Systems Biology, George Mason University, VA 20110, USA.
10
SENS Research Foundation, 1 Beaconsfield Terrace, Cambridge, CB2 3EH, UK.
11
Department of Immunobiology, Yale School of Medicine, New Haven, CT 06520, USA.
12
ActuRx, 92330 Sceaux, France.
13
Gero Limited, International Commerce Center, Kowloon, Hong Kong.
14
The Shraga Segal Department of Microbiology, Immunology and Genetics, Center for Multidisciplinary Research on Aging, Ben-Gurion University of the Negev, POB 653, 8410501, Beer-Sheva, Israel.
15
Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, Bologna, Italy.
16
Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
17
Department of Medicine, Research Center on Aging, Graduate Program in Immunology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, Quebec, Canada.
18
Nestlé Institute of Health Sciences, EPFL Innovation Park, 1015 Lausanne, Switzerland.
19
Institute of Healthy Ageing, and Department of Genetics, Evolution and Environment, University College London, London, UK.
20
Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
21
Department of Biology, University of Rochester, Rochester, NY 14627, USA.
22
Nutrition and Metabolic Health Group, Nestlé Institute of Health Sciences, CH-1015 Lausanne, Switzerland.
23
Open Research Department, L'Oreal, 93600 Aulnay-sous-Bois, France.
24
Tulane Center for Aging and Department of Medicine, Tulane University Health Sciences Center, SL-12, New Orleans, LA 70112, USA.
25
Department of Pathology, University of Washington, Seattle, WA 98195, USA.
26
Buck Institute for Research on Aging, Novato, CA 94945, USA.
27
Department of the Integrated Prevention Programs, Federal State Institution "National Research Center for Preventive Medicine" of the Ministry of Healthcare of the Russian Federation, 101990, Moscow, Russia.
28
Department of Biological Sciences, University of Lethbridge, Lethbridge, Alberta, T1K 3M4, Canada.
29
Longevity Institute and Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
30
Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
31
Integrative Genomics of Ageing Group, Institute of Ageing and Chronic Disease, University of Liverpool, Liverpool, UK.
32
Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, MA 02115, USA.
33
Department of Medicine, Dalhousie University, Centre for Health Care of the Elderly-Suite 1305, 5955 Veterans' Memorial Lane Halifax, Nova Scotia, B3H 2E1 Canada.
34
Biomedical Cluster, Skolkovo Foundation, Skolkovo, Russia.
35
Institute of Molecular Genetics of Russian Academy of Sciences, Moscow, Russia.
36
Voronezh State University, Voronezh, Russia.
37
Computer Technologies Lab, ITMO University, St. Petersburg 197101, Russia.
38
Institute for Systems Genomics, School of Medicine, University of Connecticut Health, Farmington, CT 06030, USA.
39
Centre of Medical Basic Research, Medical Faculty, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.
40
Department of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Moscow, Russia.
41
Department of Biochemistry, University of California at Riverside, Riverside, CA 92521, USA.
42
Institute of Cytology and Genetics of Siberian Branch of Russian Academy of Sciences, Novosibirsk, Russia.
43
Life Extension, Ft. Lauderdale, FL 33308, USA.
44
Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089, USA.
45
Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, NY 14263, USA.
46
BioTime, Inc., Alameda, CA 94501, USA.
47
Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, RWTH Aachen University, Aachen, Germany.
48
Center for Life Sciences Nazarbayev University, Astana, Kazakhstan.

KEYWORDS:

aging; biomarkers; epigenetics; geroprotectors; longevity; transcriptomics

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