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J Heart Lung Transplant. 2009 Jan;28(1):101-3. doi: 10.1016/j.healun.2008.10.002.

Recovery from anthracycline cardiomyopathy after long-term support with a continuous flow left ventricular assist device.

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Department of Cardiology, Alfred Hospital, Victoria, Australia.


We report the clinical course of a 16-year-old girl in remission from non-Hodgkin's lymphoma who presented in cardiogenic shock due to a severe anthracycline cardiomyopathy. The patient was initially stabilized using central extracorporeal membrane oxygenation support, followed by conversion to a left ventricular assist device. Unexpected evidence of cardiac recovery 9 months after implant enabled device weaning during a 3-month period, culminating in successful device explantation 1 year after implant. The patient survives 18 months after explant in New York Heart Association class I, on conventional heart failure medical management and metabolic therapy.

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