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Leuk Res. 2017 Feb;53:8-12. doi: 10.1016/j.leukres.2016.11.011. Epub 2016 Nov 24.

Aplastic Anemia and MDS International Foundation (AAMDSIF): Bone marrow failure disease scientific symposium 2016.

Author information

1
Section of Hematology, Department of Internal Medicine, Yale University, 333 Cedar Street, PO. Box 208028, New Haven, CT, 06520-8028, United States. Electronic address: amer.zeidan@yale.edu.
2
Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, United States. Electronic address: minoo.battiwalla@nih.gov.
3
Aplastic Anemia and Myelodysplastic Syndrome International Foundation, 4330 East West Highway, Suite 230, Bethesda, MD, United States.
4
Hematology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 10 Center Drive, Bethesda, MD, 20892, United States. Electronic address: winklert@nhlbi.nih.gov.

Abstract

Patients with acquired and inherited bone marrow failure syndromes (BMFS) have ineffective hematopoiesis due to impairments of the hematopoietic stem cell compartment. Common manifestations of BMFS include varying degrees of peripheral blood cytopenias and, sometimes, progression to acute myelogenous leukemia. Research efforts have been made all over the world to improve understanding of the pathogenesis of these diseases and their clinical implications. The Aplastic Anemia and MDS International Foundation (AAMDSIF) is an independent nonprofit organization whose mission is to help patients and family members cope with BMFS. Here, we summarize recent scientific discoveries in several BMFS that were presented at the fifth International Bone Marrow Failure Disease Scientific Symposium 2016 that AAMDSIF sponsored on March 17-18, 2016, in Rockville, Maryland.

KEYWORDS:

Aplastic anemia; Bone marrow failure; Hematopoietic stem cell transplantation; Immunobiology; Myelodysplastic syndromes; Novel therapies

PMID:
27923195
DOI:
10.1016/j.leukres.2016.11.011
[Indexed for MEDLINE]
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