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Pediatr Radiol. 2016 Nov;46(12):1630-1644. Epub 2016 Sep 22.

Clinical and imaging considerations in primary immunodeficiency disorders: an update.

Author information

1
Department of Pediatrics, University of North Carolina at Chapel Hill, 030 MacNider Hall, CB#7231, Chapel Hill, NC, 27599, USA. eveline.wu@unc.edu.
2
Department of Diagnostic Radiology, Yale School of Medicine, New Haven, CT, USA.
3
Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
4
Division of Pediatric Radiology, Duke University Medical Center, Durham, NC, USA.
5
Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.
6
Department of Immunology, Duke University School of Medicine, Durham, NC, USA.

Abstract

Primary immunodeficiencies are a group of genetically determined disorders with diverse presentations. The purpose of this review is to provide a practical and brief description of a select number of these diseases and to discuss the important role the radiologist can have in making an early diagnosis and in detecting and following disease complications. The role of diagnostic imaging and informed performance and interpretation are vital in the diagnosis, surveillance and management of all primary immunodeficiency disorders.

KEYWORDS:

Adults; Children; Computed tomography; Immunodeficiency Magnetic resonance imaging; Primary immunodeficiency disease; Radiography

PMID:
27655432
PMCID:
PMC5083248
DOI:
10.1007/s00247-016-3684-x
[Indexed for MEDLINE]
Free PMC Article
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