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Eur J Clin Invest. 2016 Nov;46(11):940-946. doi: 10.1111/eci.12672. Epub 2016 Oct 1.

Impact of anthropometric cut-off values in determining the prevalence of metabolic alterations.

Author information

1
Department of Endocrinology and Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
2
Liver Research Unit, Medica Sur Clinic & Foundation, Mexico City, Mexico.
3
Unidad de Genómica de Poblaciones Aplicada a la Salud, Facultad de Química, Universidad Nacional Autónoma de México, Instituto Nacional de Medicina Genómica (INMEGEN), Tlalpan, Mexico.
4
Liver Research Unit, Medica Sur Clinic & Foundation, Mexico City, Mexico. nmendez@medicasur.org.mx.

Abstract

BACKGROUND:

The prevalence of obesity has increased worldwide in parallel with associated metabolic disturbances such as diabetes and non-alcoholic fatty liver disease.

OBJECTIVE:

The objective of this article is to underscore discrepancies in the standard anthropometric cut-off values and the presence of metabolic disturbances including diabetes and non-alcoholic fatty liver disease caused by biological and ethnic variations.

MATERIALS AND METHODS:

We performed a literature review regarding the diagnosis and prevalence of obesity, diabetes, metabolic syndrome and non-alcoholic fatty liver disease and about the different available indicators to define obesity.

RESULTS:

There is an ongoing epidemic of these chronic diseases, partially attributed to the increased prevalence of obesity. The available markers to indicate adiposity are imperfect, and the selection of accurate cut-off points is still not clear.

CONCLUSION:

Methods to quantify adiposity that are useful in clinical practice should be developed to better classify individuals and to reflect metabolic risk more appropriately.

KEYWORDS:

Adiposity; diabetes; metabolic syndrome; non-alcoholic fatty liver disease; obesity

PMID:
27600089
DOI:
10.1111/eci.12672
[Indexed for MEDLINE]

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