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J ECT. 2017 Mar;33(1):52-57. doi: 10.1097/YCT.0000000000000348.

Computer-Assisted Cognitive Behavior Therapy to Prevent Relapse Following Electroconvulsive Therapy.

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1
From the Department of Psychiatry, Yale School of Medicine, New Haven, CT.

Abstract

OBJECTIVE:

The goal of this study was to explore the feasibility and potential efficacy of providing computer-assisted cognitive behavior therapy (CCBT) after an index course of electroconvulsive therapy (ECT) to prevent relapse.

METHODS:

In an open-label trial, subjects with major depressive episode who achieved response or remission after an acute treatment with ECT were recruited to enroll in a 9-module CCBT course. Subjects completed the CCBT modules in their own home at their own pace, but were asked to do at least 1 lesson per week, such that all 9 lessons would be completed in the first 2 months. Depression severity and relapse were monitored during the 6 months after ECT.

RESULTS:

Fifteen subjects (10 responders and 5 remitters) enrolled in the study and logged onto the CCBT course. The mean (SD) number of online lessons completed was 7.6 (1.7) or 84% of the total lessons and the mean (SD) time spent working online was 8.4 (3.9) hours. During the first 2 months (the prescribed time period), the mean (SD) number of lessons completed was 6.5 (1.8), or 72% and the mean (SD) time spent working online was 6.8 (3.2) hours. Of the entire sample of responders and remitters (n = 15), 5 (33%) relapsed at 6 months. Of the 5 remitters, none relapsed during this time period.

CONCLUSIONS:

Our results provide preliminary evidence that CCBT is feasible following ECT. Large controlled trials are needed to definitively assess whether this strategy is efficacious in preventing relapse.

PMID:
27564424
PMCID:
PMC5315599
[Available on 2018-03-01]
DOI:
10.1097/YCT.0000000000000348
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