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J Clin Neurosci. 2016 Sep;31:205-7. doi: 10.1016/j.jocn.2016.02.023. Epub 2016 Apr 16.

Melanotic neuroectodermal tumor of infancy.

Author information

1
Department of Diagnostic Radiology, Yale School of Medicine, BOX 208042, Tompkins East 2, 333 Cedar Street, New Haven, CT 06520-8042, USA.
2
Department of Pathology, Yale School of Medicine, New Haven, CT, USA.
3
Department of Diagnostic Radiology, Yale School of Medicine, BOX 208042, Tompkins East 2, 333 Cedar Street, New Haven, CT 06520-8042, USA. Electronic address: ajay.malhotra@yale.edu.

Abstract

Melanotic neuroectodermal tumor of infancy (MNTI) is a rare pigmented craniofacial tumor of newborns and infants. We report the imaging findings of a 3-month old male patient with a maxillary MNTI. Detailed discussion on imaging features on various magnetic resonance sequences and CT scan are included. Characteristic radiographic appearance is also described. MNTI, of neural crest origin, display a biphasic population of melanin containing cells and neuroblastic cells, within a moderately vascularized fibrous stroma. The child underwent complete surgical excision with no evidence of recurrence at one year follow up. MNTI is an unusual tumor occurring in early childhood with a predilection for the maxilla. Clinical findings, CT scan and MRI may allow a preoperative diagnosis.

KEYWORDS:

CT scan; Diagnostic imaging; Infants; Magnetic resonance; Maxillary tumor; Melanotic neuroectodermal tumor

PMID:
27095686
DOI:
10.1016/j.jocn.2016.02.023
[Indexed for MEDLINE]
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