Format

Send to

Choose Destination
See comment in PubMed Commons below
Minim Invasive Ther Allied Technol. 2016;25(3):162-70. doi: 10.3109/13645706.2015.1129970. Epub 2016 Feb 29.

Automatic bone removal for 3D TACE planning with C-arm CBCT: Evaluation of technical feasibility.

Author information

1
a Russell H. Morgan Department of Radiology and Radiological Science, Division of Vascular and Interventional Radiology , The Johns Hopkins Hospital , Baltimore , MD , USA ;
2
b Interventional Radiology Department , Chinese PLA General Hospital , Beijing , China ;
3
c Philips Research , Hamburg , Germany ;
4
d Service d'Imagerie Médicale, Unité de Radiologie interventionnelle et thérapeutique Vasculaire et Oncologique, Université Paris-Est Créteil, Assistance Publique-Hôpitaux de Paris, Centre Hospitalo-Universitaire Henri Mondor , France ;
5
e Yale University School of Medicine, Department of Radiology and Biomedical Imaging , New Haven , CT , USA ;
6
f U/S Imaging and Interventions (UII), Philips Research North America , Cambridge , MA , USA.

Abstract

PURPOSE:

To evaluate the technical feasibility of automatically removing the ribs and spine from C-arm cone-beam computed tomography (CBCT) images acquired during transcatheter arterial chemoembolization (TACE).

MATERIAL AND METHODS:

Fifty-eight patients (45.8 ± 5.0 years) with unresectable hepatocellular carcinoma (HCC) underwent transcatheter arterial chemoembolization and had intraprocedural CBCT imaging. Automatic bone removal was performed using model-based segmentation of the ventral cavity. Two interventional radiologists independently evaluated the performance of bone removal, remaining soft tissue retention, and general usability (where both the bone is appropriately removed while retaining soft tissue) for 3D TACE planning on a four-level (complete/excellent, adequate/good, incomplete/questionable, insufficient/bad) score. The proportion of inter-reader agreement was calculated.

RESULTS:

For ribs and spine removal, 98.3-100% and 100% of cases showed complete or adequate performance, respectively. In 96.6% of the cases, soft tissue was at least adequately retained. 91.3-93.1% of the cases demonstrated good or excellent general usability for TACE planning. Satisfactory inter-reader agreement proportion was achieved in ribs (93.1%) and spine removal (89.7%), soft tissue retention (84.5%), and general usability for TACE planning (72.4%).

CONCLUSION:

Intraprocedural automatic bone removal on CBCT images is technically feasible and offers good removal of ribs and spine while preserving soft tissue. Its clinical value needs further assessment.

KEYWORDS:

Hepatocellular carcinoma; automatic bone removal; cone-beam computed tomography; three-dimensional; transcatheter arterial chemoembolization

PMID:
26923140
PMCID:
PMC4833567
DOI:
10.3109/13645706.2015.1129970
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis Icon for PubMed Central
    Loading ...
    Support Center