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Cell. 2015 Jul 30;162(3):476-7. doi: 10.1016/j.cell.2015.06.030.

Stem Cells Show Parental Control.

Author information

1
Department of Dermatology, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: peggy.myung@yale.edu.
2
Department of Dermatology, Yale School of Medicine, New Haven, CT 06510, USA; Department of Genetics, Yale Stem Cell Center, Yale Cancer Center, Yale School of Medicine, New Haven, CT 06510, USA. Electronic address: valentina.greco@yale.edu.

Abstract

Stem cells interact with their niche to maintain an undifferentiated state. The study by Pardo-Saganta et al. shows that airway basal stem cells maintain secretory daughter cells in airway epithelia through forward regulation, suggesting that stem cells may serve as a niche for their progeny.

PMID:
26232219
DOI:
10.1016/j.cell.2015.06.030
[Indexed for MEDLINE]
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