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Sci Rep. 2015 Jul 2;5:11205. doi: 10.1038/srep11205.

HIV burden in men who have sex with men: a prospective cohort study 2007-2012.

Author information

1
1] National Institute of Drug Dependence, Health Science Center, Peking University Beijing 100191, China [2] Peking University Clinical Research Institute, Health Science Center, Peking University Beijing 100191, China [3] Takemi Program in International Health, Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
2
Center for Infectious Diseases, Beijing You'an Hospital, Capital Medical University, Beijing 100069, China.
3
School of Geography, Beijing Normal University, Beijing 100875, China.
4
National Institute of Drug Dependence, Health Science Center, Peking University Beijing 100191, China.
5
The Global Fund to fight AIDS, Tuberculosis and Malaria, 1214 Geneva, Switzerland.
6
Aaron Diamond AIDS Research Center, New York, 10016, USA.
7
Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
8
The Fenway Institute, Fenway Health, Boston, MA 02118, USA.
9
Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA.
10
Department of Biomedical Engineering, College of Engineering, Peking University, Beijing 100871, China.
11
HIV/AIDS, Tuberculosis, Malaria &Neglected Tropical Diseases, World Health Organization, 1211 Geneva 27, Switzerland.

Abstract

We conducted a prospective cohort study among HIV-negative MSM aged 18 years or older between 2007 and 2012 in Beijing, China to measure the rates of incident HIV and identify risk factors for infection. Among 5,800 participants evaluated at enrollment, we identified 486 prevalent cases of HIV (8.4%). Among the 3,625 enrollees who were HIV-negative at enrollment and completed at least one follow-up interview, we identified 440 incident cases of HIV in the follow up period: this constituted an HIV incidence rate of 7.1 per 100 person-years (95% CI: 6.4-7.7). Early treatment of syphilis may have significantly reduced risk of HIV infection (RR: 1.45, 95% CI: 1.11-1.93), while MSM presenting perfect compliance in the cohort did not show reduction in HIV infection. Our study suggested that HIV incidence has been remained high in this sample of Chinese MSM during the intensive preventive intervention, suggesting that we need to find new strategies to prevent HIV infection in this population.

PMID:
26135810
PMCID:
PMC5393284
DOI:
10.1038/srep11205
[Indexed for MEDLINE]
Free PMC Article

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