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Biol Reprod. 2015 Jun;92(6):138. doi: 10.1095/biolreprod.114.126771. Epub 2015 Apr 22.

The endometrium as a source of mesenchymal stem cells for regenerative medicine.

Author information

1
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut.
2
Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut hugh.taylor@yale.edu.

Abstract

Stem cell therapies have opened new frontiers in medicine with the possibility of regenerating lost or damaged cells. Embryonic stem cells, induced pluripotent stem cells, hematopoietic stem cells, and mesenchymal stem cells have been used to derive mature cell types for tissue regeneration and repair. However, the endometrium has emerged as an attractive, novel source of adult stem cells that are easily accessed and demonstrate remarkable differentiation capacity. In this review, we summarize our current understanding of endometrial stem cells and their therapeutic potential in regenerative medicine.

KEYWORDS:

cell transplantation; endometrium; mesenchymal stem cells; regenerative medicine; stem cells

PMID:
25904012
PMCID:
PMC4652610
DOI:
10.1095/biolreprod.114.126771
[Indexed for MEDLINE]
Free PMC Article
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