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J Clin Pharmacol. 2015 Oct;55(10):1119-24. doi: 10.1002/jcph.520. Epub 2015 May 28.

Antiretroviral therapy-induced toxicity is associated with increased mRNA expression of telomerase.

Author information

1
Department of Pediatrics, Yale School of Medicine, New Haven, CT, USA.
2
Department of Cell Physiology and Pharmacology, School of Biological Sciences, University of Leicester, Leicester, UK.
3
Department of Internal Medicine, University of São Paulo Medical School at Ribeirão Preto, São Paulo, Brazil.
4
Department of Epidemiology & Public Health, Yale School of Medicine, New Haven, CT, USA.
5
Department of Pharmacology, New Haven, CT, USA.

KEYWORDS:

antiretroviral therapy; immune activation; mitochondrial toxicity; telomerase; telomere length

PMID:
25903721
PMCID:
PMC4558235
DOI:
10.1002/jcph.520
[Indexed for MEDLINE]
Free PMC Article

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