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J Thorac Oncol. 2014 Sep;9(9 Suppl 2):S102-9. doi: 10.1097/JTO.0000000000000294.

Approaching the patient with an anterior mediastinal mass: a guide for clinicians.

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*Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX; and †Division of Thoracic Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT.


Anterior mediastinal masses are relatively uncommon, include a wide variety of entities, and often pose a diagnostic challenge for clinicians. In this article, available data is assembled in a clinically oriented manner to develop a structured approach to evaluation of these patients. Attention to age and gender, combined with identification of certain radiographic and clinical characteristics, allows a presumptive diagnosis to be established in most patients. This structure efficiently guides what additional workup is needed.

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