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J Am Med Dir Assoc. 2015 Mar;16(3):194-9. doi: 10.1016/j.jamda.2014.08.017. Epub 2014 Oct 11.

Physical frailty predicts incident depressive symptoms in elderly people: prospective findings from the Obu Study of Health Promotion for the Elderly.

Author information

1
Department of Functioning Activation, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Aichi, Japan. Electronic address: makizako@ncgg.go.jp.
2
Department of Functioning Activation, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Aichi, Japan.
3
Department of Functioning Activation, Center for Gerontology and Social Science, National Center for Geriatrics and Gerontology, Aichi, Japan; Japan Society for the Promotion of Science, Tokyo, Japan.
4
Aging, Mobility, and Cognitive Neuroscience Laboratory, Department of Physical Therapy, University of British Columbia, Vancouver, British Columbia, Canada; Djavad Mowafaghian Center, for Brain Health, University of British Columbia, Vancouver, British Columbia, Canada; Center for Hip Health and Mobility, Vancouver Coastal Health Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.
5
Research Institute, National Center for Geriatrics and Gerontology, Aichi, Japan.

Abstract

OBJECTIVE:

The purpose of this study was to determine whether frailty is an important and independent predictor of incident depressive symptoms in elderly people without depressive symptoms at baseline.

DESIGN:

Fifteen-month prospective study.

SETTING:

General community in Japan.

PARTICIPANTS:

A total of 3025 community-dwelling elderly people aged 65 years or over without depressive symptoms at baseline.

MEASUREMENTS:

The self-rated 15-item Geriatric Depression Scale was used to assess symptoms of depression with a score of 6 or more at baseline and 15-month follow-up. Participants underwent a structural interview designed to obtain demographic factors and frailty status, and completed cognitive testing with the Mini-Mental State Examination and physical performance testing with the Short Physical Performance Battery as potential predictors.

RESULTS:

At a 15-month follow-up survey, 226 participants (7.5%) reported the development of depressive symptoms. We found that frailty and poor self-rated general health (adjusted odds ratio 1.86, 95% confidence interval 1.30-2.66, P < .01) were independent predictors of incident depressive symptoms. The odds ratio for depressive symptoms in participants with frailty compared with robust participants was 1.86 (95% confidence interval 1.05-3.28, P = .03) after adjusting for demographic factors, self-rated general health, behavior, living arrangements, Mini-Mental State Examination, Short Physical Performance Battery, and Geriatric Depression Scale scores at baseline.

CONCLUSIONS:

Our findings suggested that frailty and poor self-rated general health were independent predictors of depressive symptoms in community-dwelling elderly people.

KEYWORDS:

Geriatric Depression Scale; cognitive function; frailty; physical performance; self-rated health

PMID:
25307294
DOI:
10.1016/j.jamda.2014.08.017
[Indexed for MEDLINE]

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