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Curr Biol. 2014 Sep 22;24(18):R831-R833. doi: 10.1016/j.cub.2014.08.004.

Membrane fusion: HAP2 protein on a short leash.

Author information

1
Department of Molecular, Cellular and Developmental Biology, University of California Santa Barbara, Santa Barbara, CA 93106, USA. Electronic address: eduardo.orias@lifesci.ucsb.edu.

Abstract

Localized membrane fusion in the Tetrahymena conjugation junction generates pores that provide transient cytoplasmic continuity between the two partner cells. Without male gamete-specific fusion protein HAP2/GSC1, pores fail to form, fertilization is blocked, and pair stability is compromised.

PMID:
25247352
DOI:
10.1016/j.cub.2014.08.004
[Indexed for MEDLINE]
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