Format

Send to

Choose Destination
Ann Otol Rhinol Laryngol. 2014 Nov;123(11):765-8. doi: 10.1177/0003489414538398. Epub 2014 Jun 19.

Hajek revisited: a histological examination of the quadrangular membrane.

Author information

1
Department of Surgery, Section of Otolaryngology, Yale University, New Haven, Connecticut, USA nwanmegha.young@yale.edu.
2
Department of Surgery, Section of Otolaryngology, Yale University, New Haven, Connecticut, USA Department of Surgery, Section of Otolaryngology, Cairo University, Egypt.
3
Department of Surgery, Section of Otolaryngology, Yale University, New Haven, Connecticut, USA.

Abstract

OBJECTIVE:

The predictability of laryngeal cancer spread is due in part to connective tissue membranes. These membranes function as barriers to cancer and divide the larynx into subunits. The field of laryngeal conservation surgery is based on these concepts. The quadrangular membrane plays an important role, hindering the lateral spread of cancer in the larynx. The composition of this membrane has not been well described in the literature. In this study, we examine basic characteristics of the quadrangular membrane using histological techniques.

METHODS:

Whole organ sections of the larynx were used. These sections were examined under a microscope with stains specific for collagen and elastin.

RESULTS:

Examination of the sections revealed that the quadrangular membrane is made up of closely woven undulating collagen and elastic fibers.

CONCLUSION:

The quadrangular membrane is a fibroelastic structure providing a barrier to cancer spread.

KEYWORDS:

Laryngeal neoplasm/physiology; laryngeal anatomy

PMID:
24947408
DOI:
10.1177/0003489414538398
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center