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Gastrointest Endosc. 2014 Dec;80(6):1022-9. doi: 10.1016/j.gie.2014.04.001. Epub 2014 May 20.

Efficiency of pancreatic duct stenting therapy in children with chronic pancreatitis.

Author information

1
Department of Gastroenterology, Hepatology and Feeding Disorders, The Children's Memorial Health Institute, Warsaw, Poland.
2
Endoterapia, Warsaw, Poland.

Abstract

BACKGROUND:

Chronic pancreatitis (CP) is a rare disease in childhood. Although ERCP is commonly performed in children, the effect of pancreatic duct stenting therapy in children with CP is unknown.

OBJECTIVE:

To investigate the efficacy of pancreatic duct stenting in children with CP.

DESIGN:

Retrospective analysis.

SETTING:

National referral center.

PATIENTS:

A total of 208 children with CP hospitalized between 1988 and 2012.

INTERVENTIONS:

ERCP with pancreatic duct stenting.

MAIN OUTCOME MEASUREMENTS:

Results of endoscopic therapy and number of pancreatitis episodes per year before and after treatment.

RESULTS:

A total of 223 pancreatic duct stenting procedures were performed in 72 children. The median number of stent replacements was 3 (range 1-21). A statistically significant decrease in the number of pancreatitis episodes per year was observed: from 1.75 to 0.23 after endoscopic treatment (P < .05). Pancreatic duct stenting was performed more frequently in patients with hereditary pancreatitis (61.5%) and in children with CP and anatomic anomalies of the pancreatic duct (65%; P < .05).

LIMITATIONS:

Retrospective analysis with the assessment of adverse events based on medical history.

CONCLUSION:

Pancreatic duct stenting therapy is a safe and effective procedure in children with CP. This therapy should be recommended especially for children with hereditary pancreatitis and patients with anatomic anomalies of the pancreatic duct.

PMID:
24852105
DOI:
10.1016/j.gie.2014.04.001
[Indexed for MEDLINE]
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