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Cell Stem Cell. 2014 Jan 2;14(1):3-4. doi: 10.1016/j.stem.2013.12.003.

ESCaping rejection: A step forward for embryonic-stem-cell-based regenerative medicine.

Author information

1
Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA.
2
Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA; Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address: richard.flavell@yale.edu.

Abstract

The use of human embryonic stem cells (hESCs) for regenerative medicine currently faces several hurdles, including immune rejection of transplanted cells. Now in Cell Stem Cell, Rong et al. (2014) describe a strategy to protect hESCs from immune rejection while avoiding systemic immunosuppression, potentially facilitating clinical implementation of hESC-based therapies.

PMID:
24388169
DOI:
10.1016/j.stem.2013.12.003
[Indexed for MEDLINE]
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