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Dev Cell. 2013 Apr 29;25(2):113-4. doi: 10.1016/j.devcel.2013.04.009.

Linking morphogen and chromatin in the hair follicle.

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1
Department of Genetics, Yale Stem Cell Center, Yale School of Medicine, New Haven, CT 06510, USA.

Abstract

In this issue of Developmental Cell, Xiong et al. (2013) identify a critical role for the chromatin remodeler Brg1 in hair follicle stem cell maintenance and epidermal repair. Brg1 interacts with the Shh signaling pathway to create a positive feedback loop that fuels hair follicle growth.

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